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PDE8B phosphodiesterase 8B [ Coturnix japonica (Japanese quail) ]

Gene ID: 107305928, updated on 14-Mar-2024

Summary

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Gene symbol
PDE8B
Gene description
phosphodiesterase 8B
See related
Ensembl:ENSCJPG00005007937
Gene type
protein coding
RefSeq status
MODEL
Organism
Coturnix japonica
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Perdicinae; Coturnix
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Z
Exon count:
22
Annotation release Status Assembly Chr Location
101 current Coturnix japonica 2.1 (GCF_001577835.2) Z NC_029547.1 (11983886..12049229)

Chromosome Z - NC_029547.1Genomic Context describing neighboring genes Neighboring gene angiogenic factor with G-patch and FHA domains 1 Neighboring gene uncharacterized LOC107305927 Neighboring gene small nucleolar RNA SNORA47 Neighboring gene WD repeat domain 41 Neighboring gene uncharacterized LOC107305879 Neighboring gene orthopedia homeobox

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_029547.1 Chromosome Z Reference Coturnix japonica 2.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 3',5'-cyclic-AMP phosphodiesterase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Coturnix japonica Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Coturnix japonica 2.1 Primary Assembly

Genomic

  1. NC_029547.1 Reference Coturnix japonica 2.1 Primary Assembly

    Range
    11983886..12049229
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_032441227.1 → XP_032297118.1  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X1

    UniProtKB/TrEMBL
    A0A8C2T5V5
    Conserved Domains (4) summary
    COG2202
    Location:148 → 360
    PAS; PAS domain [Signal transduction mechanisms]
    pfam00233
    Location:604 → 856
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
    pfam08629
    Location:1 → 46
    PDE8; PDE8 phosphodiesterase
    pfam13426
    Location:261 → 358
    PAS_9; PAS domain

  2. XM_032441229.1 → XP_032297120.1  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X5

    UniProtKB/TrEMBL
    A0A8C2T8A3
    Related
    ENSCJPP00005008958.1, ENSCJPT00005013467.1
    Conserved Domains (4) summary
    COG2202
    Location:122 → 340
    PAS; PAS domain [Signal transduction mechanisms]
    pfam00233
    Location:584 → 836
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
    pfam08629
    Location:1 → 46
    PDE8; PDE8 phosphodiesterase
    pfam13426
    Location:241 → 338
    PAS_9; PAS domain

  3. XM_032441228.1 → XP_032297119.1  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X2

    UniProtKB/TrEMBL
    A0A8C2T5V5
    Conserved Domains (4) summary
    COG2202
    Location:147 → 359
    PAS; PAS domain [Signal transduction mechanisms]
    pfam00233
    Location:603 → 855
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
    pfam08629
    Location:1 → 46
    PDE8; PDE8 phosphodiesterase
    pfam13426
    Location:260 → 357
    PAS_9; PAS domain

  4. XM_015848637.2 → XP_015704123.1  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X3

    UniProtKB/TrEMBL
    A0A8C2T5V5
    Conserved Domains (5) summary
    COG0745
    Location:135 → 216
    OmpR; DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain [Signal transduction mechanisms, Transcription]
    cd00130
    Location:265 → 357
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam00233
    Location:598 → 850
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
    pfam08629
    Location:1 → 46
    PDE8; PDE8 phosphodiesterase
    pfam13426
    Location:261 → 358
    PAS_9; PAS domain

  5. XM_015848638.2 → XP_015704124.1  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X4

    UniProtKB/TrEMBL
    A0A8C2T5V5, A0A8C2Y8V6
    Related
    ENSCJPP00005008952.1, ENSCJPT00005013461.1
    Conserved Domains (5) summary
    COG0745
    Location:134 → 215
    OmpR; DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain [Signal transduction mechanisms, Transcription]
    cd00130
    Location:264 → 356
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam00233
    Location:597 → 849
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
    pfam08629
    Location:1 → 46
    PDE8; PDE8 phosphodiesterase
    pfam13426
    Location:260 → 357
    PAS_9; PAS domain
Nucleotide Protein
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