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FYN FYN proto-oncogene, Src family tyrosine kinase [ Acinonyx jubatus (cheetah) ]

Gene ID: 106968910, updated on 11-Apr-2024

Summary

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Gene symbol
FYN
Gene description
FYN proto-oncogene, Src family tyrosine kinase
Gene type
protein coding
RefSeq status
MODEL
Organism
Acinonyx jubatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Acinonychinae; Acinonyx
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: B2
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2023_04 current VMU_Ajub_asm_v1.0 (GCF_027475565.1) B2 NC_069385.1 (50636866..50850618)

Chromosome B2 - NC_069385.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC128315546 Neighboring gene 60S ribosomal protein L39-like Neighboring gene uncharacterized LOC128315547 Neighboring gene uncharacterized LOC128315548 Neighboring gene uncharacterized LOC128315549 Neighboring gene TRAF3 interacting protein 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_069385.1 Chromosome B2 Reference VMU_Ajub_asm_v1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables non-membrane spanning protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in T cell receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in innate immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extrinsic component of cytoplasmic side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tyrosine-protein kinase Fyn

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_027475565.1-RS_2023_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference VMU_Ajub_asm_v1.0

Genomic

  1. NC_069385.1 Reference VMU_Ajub_asm_v1.0

    Range
    50636866..50850618
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027057070.2 → XP_026912871.1  tyrosine-protein kinase Fyn isoform X1

    UniProtKB/TrEMBL
    A0A6J1Z6I8
    Conserved Domains (3) summary
    cd10418
    Location:145 → 245
    SH2_Src_Fyn_isoform_a_like; Src homology 2 (SH2) domain found in Fyn isoform a like proteins
    cd12006
    Location:85 → 140
    SH3_Fyn_Yrk; Src homology 3 domain of Fyn and Yrk Protein Tyrosine Kinases
    cd05070
    Location:261 → 534
    PTKc_Fyn; Catalytic domain of the Protein Tyrosine Kinase, Fyn

  2. XM_027057076.2 → XP_026912877.1  tyrosine-protein kinase Fyn isoform X2

    UniProtKB/TrEMBL
    A0A6J1Z5W6
    Conserved Domains (3) summary
    cd10368
    Location:145 → 245
    SH2_Src_Fyn; Src homology 2 (SH2) domain found in Fyn
    cd12006
    Location:85 → 140
    SH3_Fyn_Yrk; Src homology 3 domain of Fyn and Yrk Protein Tyrosine Kinases
    cd05070
    Location:258 → 531
    PTKc_Fyn; Catalytic domain of the Protein Tyrosine Kinase, Fyn

  3. XM_027057071.2 → XP_026912872.1  tyrosine-protein kinase Fyn isoform X1

    UniProtKB/TrEMBL
    A0A6J1Z6I8
    Conserved Domains (3) summary
    cd10418
    Location:145 → 245
    SH2_Src_Fyn_isoform_a_like; Src homology 2 (SH2) domain found in Fyn isoform a like proteins
    cd12006
    Location:85 → 140
    SH3_Fyn_Yrk; Src homology 3 domain of Fyn and Yrk Protein Tyrosine Kinases
    cd05070
    Location:261 → 534
    PTKc_Fyn; Catalytic domain of the Protein Tyrosine Kinase, Fyn

  4. XM_027057072.2 → XP_026912873.1  tyrosine-protein kinase Fyn isoform X1

    UniProtKB/TrEMBL
    A0A6J1Z6I8
    Conserved Domains (3) summary
    cd10418
    Location:145 → 245
    SH2_Src_Fyn_isoform_a_like; Src homology 2 (SH2) domain found in Fyn isoform a like proteins
    cd12006
    Location:85 → 140
    SH3_Fyn_Yrk; Src homology 3 domain of Fyn and Yrk Protein Tyrosine Kinases
    cd05070
    Location:261 → 534
    PTKc_Fyn; Catalytic domain of the Protein Tyrosine Kinase, Fyn

  5. XM_015065371.3 → XP_014920857.1  tyrosine-protein kinase Fyn isoform X1

    UniProtKB/TrEMBL
    A0A6J1Z6I8
    Conserved Domains (3) summary
    cd10418
    Location:145 → 245
    SH2_Src_Fyn_isoform_a_like; Src homology 2 (SH2) domain found in Fyn isoform a like proteins
    cd12006
    Location:85 → 140
    SH3_Fyn_Yrk; Src homology 3 domain of Fyn and Yrk Protein Tyrosine Kinases
    cd05070
    Location:261 → 534
    PTKc_Fyn; Catalytic domain of the Protein Tyrosine Kinase, Fyn

  6. XM_027057075.2 → XP_026912876.1  tyrosine-protein kinase Fyn isoform X1

    UniProtKB/TrEMBL
    A0A6J1Z6I8
    Conserved Domains (3) summary
    cd10418
    Location:145 → 245
    SH2_Src_Fyn_isoform_a_like; Src homology 2 (SH2) domain found in Fyn isoform a like proteins
    cd12006
    Location:85 → 140
    SH3_Fyn_Yrk; Src homology 3 domain of Fyn and Yrk Protein Tyrosine Kinases
    cd05070
    Location:261 → 534
    PTKc_Fyn; Catalytic domain of the Protein Tyrosine Kinase, Fyn
Nucleotide Protein
Heading Accession and Version

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