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Fyn Fyn proto-oncogene [ Mus musculus (house mouse) ]

Gene ID: 14360, updated on 8-Feb-2024

Summary

Official Symbol
Fynprovided by MGI
Official Full Name
Fyn proto-oncogeneprovided by MGI
Primary source
MGI:MGI:95602
See related
Ensembl:ENSMUSG00000019843 AllianceGenome:MGI:95602
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Enables several functions, including cytoskeletal protein binding activity; protein tyrosine kinase activity; and transmembrane transporter binding activity. Involved in several processes, including negative regulation of dendritic spine maintenance; positive regulation of protein targeting to membrane; and positive regulation of tyrosine phosphorylation of STAT protein. Acts upstream of or within several processes, including cellular response to growth factor stimulus; nervous system development; and protein phosphorylation. Located in several cellular components, including Schaffer collateral - CA1 synapse; actin filament; and postsynaptic density. Is expressed in several structures, including alimentary system; central nervous system; cranial nerve; genitourinary system; and sensory organ. Used to study skin disease and skin squamous cell carcinoma. Human ortholog(s) of this gene implicated in Alzheimer's disease and schizophrenia. Orthologous to human FYN (FYN proto-oncogene, Src family tyrosine kinase). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E18 (RPKM 23.2), CNS E14 (RPKM 20.7) and 27 other tissues See more
Orthologs
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Genomic context

See Fyn in Genome Data Viewer
Location:
10 B1; 10 20.51 cM
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (39245735..39441377)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (39369743..39565381)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 31562 Neighboring gene STARR-positive B cell enhancer mm9_chr10:39089323-39089624 Neighboring gene predicted gene, 31616 Neighboring gene STARR-seq mESC enhancer starr_26390 Neighboring gene STARR-seq mESC enhancer starr_26392 Neighboring gene predicted gene 16364 Neighboring gene STARR-seq mESC enhancer starr_26396 Neighboring gene RIKEN cDNA E130307A14 gene Neighboring gene predicted gene, 40627 Neighboring gene STARR-seq mESC enhancer starr_26400 Neighboring gene TRAF3 interacting protein 2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • MGC115870

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables CD4 receptor binding ISO
Inferred from Sequence Orthology
more info
 
enables CD8 receptor binding ISO
Inferred from Sequence Orthology
more info
 
enables G protein-coupled receptor binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables T cell receptor binding ISO
Inferred from Sequence Orthology
more info
 
enables alpha-tubulin binding IDA
Inferred from Direct Assay
more info
PubMed 
enables disordered domain specific binding ISO
Inferred from Sequence Orthology
more info
 
enables enzyme binding ISO
Inferred from Sequence Orthology
more info
 
enables ephrin receptor binding ISO
Inferred from Sequence Orthology
more info
 
enables growth factor receptor binding ISO
Inferred from Sequence Orthology
more info
 
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
enables kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables non-membrane spanning protein tyrosine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables non-membrane spanning protein tyrosine kinase activity ISO
Inferred from Sequence Orthology
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables peptide hormone receptor binding ISO
Inferred from Sequence Orthology
more info
 
enables phosphatidylinositol 3-kinase binding ISO
Inferred from Sequence Orthology
more info
 
enables phospholipase activator activity ISO
Inferred from Sequence Orthology
more info
 
enables phospholipase binding ISO
Inferred from Sequence Orthology
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables protein kinase activity ISO
Inferred from Sequence Orthology
more info
 
enables protein tyrosine kinase activity EXP
Inferred from Experiment
more info
PubMed 
enables protein tyrosine kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables protein tyrosine kinase activity IGI
Inferred from Genetic Interaction
more info
PubMed 
enables protein tyrosine kinase activity ISO
Inferred from Sequence Orthology
more info
 
enables protein tyrosine kinase activity TAS
Traceable Author Statement
more info
 
enables protein-containing complex binding ISO
Inferred from Sequence Orthology
more info
 
enables scaffold protein binding ISO
Inferred from Sequence Orthology
more info
 
enables signaling receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables signaling receptor binding ISO
Inferred from Sequence Orthology
more info
 
enables tau protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
enables transmembrane transporter binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables tubulin binding IDA
Inferred from Direct Assay
more info
PubMed 
enables type 5 metabotropic glutamate receptor binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in T cell receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in T cell receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within activated T cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within adaptive immune response IEA
Inferred from Electronic Annotation
more info
 
involved_in cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within cell surface receptor signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
involved_in cellular response to L-glutamate ISO
Inferred from Sequence Orthology
more info
 
involved_in cellular response to amyloid-beta ISO
Inferred from Sequence Orthology
more info
 
involved_in cellular response to glycine ISO
Inferred from Sequence Orthology
more info
 
involved_in cellular response to hydrogen peroxide ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within cellular response to platelet-derived growth factor stimulus IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within cellular response to transforming growth factor beta stimulus IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within dendrite morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within detection of mechanical stimulus involved in sensory perception of pain IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within forebrain development IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within forebrain development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within gene expression IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in heart process IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in heart process ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within immune system process IEA
Inferred from Electronic Annotation
more info
 
involved_in innate immune response IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in intracellular signal transduction ISO
Inferred from Sequence Orthology
more info
 
involved_in modulation of chemical synaptic transmission IDA
Inferred from Direct Assay
more info
PubMed 
involved_in modulation of chemical synaptic transmission IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within myelination TAS
Traceable Author Statement
more info
PubMed 
involved_in negative regulation of dendritic spine maintenance IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in negative regulation of extrinsic apoptotic signaling pathway in absence of ligand ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of gene expression IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of hydrogen peroxide biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of neuron apoptotic process ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within negative regulation of protein catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within negative regulation of protein ubiquitination IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within neuron migration IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within neuron migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of neuron projection development IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within peptidyl-tyrosine phosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in peptidyl-tyrosine phosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within peptidyl-tyrosine phosphorylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in peptidyl-tyrosine phosphorylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in peptidyl-tyrosine phosphorylation ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within positive regulation of neuron projection development IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within positive regulation of protein localization to nucleus IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of protein localization to nucleus IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of protein targeting to membrane IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in positive regulation of tyrosine phosphorylation of STAT protein IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within protein autophosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of protein catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in protein phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within protein phosphorylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of protein ubiquitination IDA
Inferred from Direct Assay
more info
PubMed 
involved_in regulation of calcium ion import across plasma membrane IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within regulation of cell shape IDA
Inferred from Direct Assay
more info
PubMed 
involved_in regulation of glutamate receptor signaling pathway IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in regulation of peptidyl-tyrosine phosphorylation IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in response to amyloid-beta IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within response to ethanol IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in response to singlet oxygen ISO
Inferred from Sequence Orthology
more info
 
involved_in transmembrane receptor protein tyrosine kinase signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in Schaffer collateral - CA1 synapse IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in Schaffer collateral - CA1 synapse IMP
Inferred from Mutant Phenotype
more info
PubMed 
located_in actin filament IDA
Inferred from Direct Assay
more info
PubMed 
located_in cell body IDA
Inferred from Direct Assay
more info
PubMed 
located_in cell periphery IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol TAS
Traceable Author Statement
more info
 
located_in dendrite IMP
Inferred from Mutant Phenotype
more info
PubMed 
located_in endosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in endosome ISO
Inferred from Sequence Orthology
more info
 
located_in glial cell projection IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in glutamatergic synapse ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane raft IDA
Inferred from Direct Assay
more info
PubMed 
colocalizes_with membrane raft ISO
Inferred from Sequence Orthology
more info
 
located_in membrane raft ISO
Inferred from Sequence Orthology
more info
 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
located_in perinuclear endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
located_in perinuclear region of cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane TAS
Traceable Author Statement
more info
 
located_in postsynaptic density IMP
Inferred from Mutant Phenotype
more info
PubMed 
located_in postsynaptic density ISO
Inferred from Sequence Orthology
more info
 
is_active_in postsynaptic density, intracellular component ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
tyrosine-protein kinase Fyn
Names
Src Kinase p59
p59-Fyn
proto-oncogene c-Fyn
proto-oncogene tyrosine-protein kinase Fyn
NP_001116364.1
NP_001116365.1
NP_032080.2
XP_006512602.1
XP_006512603.1
XP_011241419.1
XP_030100741.1
XP_036011496.1
XP_036011497.1
XP_036011498.1
XP_036011499.1
XP_036011500.1
XP_036011501.1
XP_036011502.1
XP_036011503.1
XP_036011504.1
XP_036011505.1
XP_036011506.1
XP_036011507.1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001122892.1NP_001116364.1  tyrosine-protein kinase Fyn isoform b

    See identical proteins and their annotated locations for NP_001116364.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) uses an alternate in-frame exon in the coding region and differs in the 5' UTR compared to variant 1. It encodes an isoform (b) with a different and shorter internal segment compared to isoform a. Variants 2 and 3 encode the same isoform (b).
    Source sequence(s)
    BC092217, BE952821, BF662030, BQ714273
    Consensus CDS
    CCDS23788.1
    UniProtKB/Swiss-Prot
    P39688
    Related
    ENSMUSP00000115233.2, ENSMUST00000126486.8
    Conserved Domains (3) summary
    cd10368
    Location:145245
    SH2_Src_Fyn; Src homology 2 (SH2) domain found in Fyn
    cd12006
    Location:85140
    SH3_Fyn_Yrk; Src homology 3 domain of Fyn and Yrk Protein Tyrosine Kinases
    cd05070
    Location:258531
    PTKc_Fyn; Catalytic domain of the Protein Tyrosine Kinase, Fyn
  2. NM_001122893.1NP_001116365.1  tyrosine-protein kinase Fyn isoform a

    See identical proteins and their annotated locations for NP_001116365.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a).
    Source sequence(s)
    BC092217, BE952821, BF662030, BQ179147, BQ714273, M27266
    Consensus CDS
    CCDS48538.1
    UniProtKB/Swiss-Prot
    P39688, Q3TAT3, Q3U0T5, Q8K2A3
    Related
    ENSMUSP00000097547.4, ENSMUST00000099967.10
    Conserved Domains (3) summary
    cd10418
    Location:145245
    SH2_Src_Fyn_isoform_a_like; Src homology 2 (SH2) domain found in Fyn isoform a like proteins
    cd12006
    Location:85140
    SH3_Fyn_Yrk; Src homology 3 domain of Fyn and Yrk Protein Tyrosine Kinases
    cd05070
    Location:261534
    PTKc_Fyn; Catalytic domain of the Protein Tyrosine Kinase, Fyn
  3. NM_008054.2NP_032080.2  tyrosine-protein kinase Fyn isoform b

    See identical proteins and their annotated locations for NP_032080.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame exon in the coding region compared to variant 1. It encodes an isoform (b) with a different and shorter internal segment compared to isoform a. Variants 2 and 3 encode the same isoform (b).
    Source sequence(s)
    BC092217, BE952821, BF662030, BQ714273, M27266
    Consensus CDS
    CCDS23788.1
    UniProtKB/Swiss-Prot
    P39688
    Related
    ENSMUSP00000057707.7, ENSMUST00000063091.13
    Conserved Domains (3) summary
    cd10368
    Location:145245
    SH2_Src_Fyn; Src homology 2 (SH2) domain found in Fyn
    cd12006
    Location:85140
    SH3_Fyn_Yrk; Src homology 3 domain of Fyn and Yrk Protein Tyrosine Kinases
    cd05070
    Location:258531
    PTKc_Fyn; Catalytic domain of the Protein Tyrosine Kinase, Fyn

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    39245735..39441377
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036155614.1XP_036011507.1  tyrosine-protein kinase Fyn isoform X6

    UniProtKB/TrEMBL
    D3YZ57
    Related
    ENSMUSP00000118131.2, ENSMUST00000136659.2
    Conserved Domains (3) summary
    cd10368
    Location:145245
    SH2_Src_Fyn; Src homology 2 (SH2) domain found in Fyn
    cd12006
    Location:85140
    SH3_Fyn_Yrk; Src homology 3 domain of Fyn and Yrk Protein Tyrosine Kinases
    cl21453
    Location:231467
    PKc_like; Protein Kinases, catalytic domain
  2. XM_036155607.1XP_036011500.1  tyrosine-protein kinase Fyn isoform X3

    UniProtKB/Swiss-Prot
    P39688, Q3TAT3, Q3U0T5, Q8K2A3
    Conserved Domains (3) summary
    cd10418
    Location:145245
    SH2_Src_Fyn_isoform_a_like; Src homology 2 (SH2) domain found in Fyn isoform a like proteins
    cd12006
    Location:85140
    SH3_Fyn_Yrk; Src homology 3 domain of Fyn and Yrk Protein Tyrosine Kinases
    cd05070
    Location:261534
    PTKc_Fyn; Catalytic domain of the Protein Tyrosine Kinase, Fyn
  3. XM_036155610.1XP_036011503.1  tyrosine-protein kinase Fyn isoform X4

    Conserved Domains (3) summary
    cd10368
    Location:145245
    SH2_Src_Fyn; Src homology 2 (SH2) domain found in Fyn
    cd12006
    Location:85140
    SH3_Fyn_Yrk; Src homology 3 domain of Fyn and Yrk Protein Tyrosine Kinases
    cd05070
    Location:258531
    PTKc_Fyn; Catalytic domain of the Protein Tyrosine Kinase, Fyn
  4. XM_036155603.1XP_036011496.1  tyrosine-protein kinase Fyn isoform X1

    Conserved Domains (3) summary
    cd10418
    Location:184284
    SH2_Src_Fyn_isoform_a_like; Src homology 2 (SH2) domain found in Fyn isoform a like proteins
    cd12006
    Location:124179
    SH3_Fyn_Yrk; Src homology 3 domain of Fyn and Yrk Protein Tyrosine Kinases
    cd05070
    Location:300573
    PTKc_Fyn; Catalytic domain of the Protein Tyrosine Kinase, Fyn
  5. XM_036155606.1XP_036011499.1  tyrosine-protein kinase Fyn isoform X2

    Conserved Domains (3) summary
    cd10368
    Location:184284
    SH2_Src_Fyn; Src homology 2 (SH2) domain found in Fyn
    cd12006
    Location:124179
    SH3_Fyn_Yrk; Src homology 3 domain of Fyn and Yrk Protein Tyrosine Kinases
    cd05070
    Location:297570
    PTKc_Fyn; Catalytic domain of the Protein Tyrosine Kinase, Fyn
  6. XM_036155613.1XP_036011506.1  tyrosine-protein kinase Fyn isoform X5

    Conserved Domains (3) summary
    cd10368
    Location:184284
    SH2_Src_Fyn; Src homology 2 (SH2) domain found in Fyn
    cd12006
    Location:124179
    SH3_Fyn_Yrk; Src homology 3 domain of Fyn and Yrk Protein Tyrosine Kinases
    cl21453
    Location:270506
    PKc_like; Protein Kinases, catalytic domain
  7. XM_011243117.4XP_011241419.1  tyrosine-protein kinase Fyn isoform X3

    See identical proteins and their annotated locations for XP_011241419.1

    UniProtKB/Swiss-Prot
    P39688, Q3TAT3, Q3U0T5, Q8K2A3
    Conserved Domains (3) summary
    cd10418
    Location:145245
    SH2_Src_Fyn_isoform_a_like; Src homology 2 (SH2) domain found in Fyn isoform a like proteins
    cd12006
    Location:85140
    SH3_Fyn_Yrk; Src homology 3 domain of Fyn and Yrk Protein Tyrosine Kinases
    cd05070
    Location:261534
    PTKc_Fyn; Catalytic domain of the Protein Tyrosine Kinase, Fyn
  8. XM_036155612.1XP_036011505.1  tyrosine-protein kinase Fyn isoform X4

    Conserved Domains (3) summary
    cd10368
    Location:145245
    SH2_Src_Fyn; Src homology 2 (SH2) domain found in Fyn
    cd12006
    Location:85140
    SH3_Fyn_Yrk; Src homology 3 domain of Fyn and Yrk Protein Tyrosine Kinases
    cd05070
    Location:258531
    PTKc_Fyn; Catalytic domain of the Protein Tyrosine Kinase, Fyn
  9. XM_006512540.5XP_006512603.1  tyrosine-protein kinase Fyn isoform X3

    See identical proteins and their annotated locations for XP_006512603.1

    UniProtKB/Swiss-Prot
    P39688, Q3TAT3, Q3U0T5, Q8K2A3
    Conserved Domains (3) summary
    cd10418
    Location:145245
    SH2_Src_Fyn_isoform_a_like; Src homology 2 (SH2) domain found in Fyn isoform a like proteins
    cd12006
    Location:85140
    SH3_Fyn_Yrk; Src homology 3 domain of Fyn and Yrk Protein Tyrosine Kinases
    cd05070
    Location:261534
    PTKc_Fyn; Catalytic domain of the Protein Tyrosine Kinase, Fyn
  10. XM_036155609.1XP_036011502.1  tyrosine-protein kinase Fyn isoform X3

    UniProtKB/Swiss-Prot
    P39688, Q3TAT3, Q3U0T5, Q8K2A3
    Conserved Domains (3) summary
    cd10418
    Location:145245
    SH2_Src_Fyn_isoform_a_like; Src homology 2 (SH2) domain found in Fyn isoform a like proteins
    cd12006
    Location:85140
    SH3_Fyn_Yrk; Src homology 3 domain of Fyn and Yrk Protein Tyrosine Kinases
    cd05070
    Location:261534
    PTKc_Fyn; Catalytic domain of the Protein Tyrosine Kinase, Fyn
  11. XM_036155604.1XP_036011497.1  tyrosine-protein kinase Fyn isoform X1

    Conserved Domains (3) summary
    cd10418
    Location:184284
    SH2_Src_Fyn_isoform_a_like; Src homology 2 (SH2) domain found in Fyn isoform a like proteins
    cd12006
    Location:124179
    SH3_Fyn_Yrk; Src homology 3 domain of Fyn and Yrk Protein Tyrosine Kinases
    cd05070
    Location:300573
    PTKc_Fyn; Catalytic domain of the Protein Tyrosine Kinase, Fyn
  12. XM_036155608.1XP_036011501.1  tyrosine-protein kinase Fyn isoform X3

    UniProtKB/Swiss-Prot
    P39688, Q3TAT3, Q3U0T5, Q8K2A3
    Conserved Domains (3) summary
    cd10418
    Location:145245
    SH2_Src_Fyn_isoform_a_like; Src homology 2 (SH2) domain found in Fyn isoform a like proteins
    cd12006
    Location:85140
    SH3_Fyn_Yrk; Src homology 3 domain of Fyn and Yrk Protein Tyrosine Kinases
    cd05070
    Location:261534
    PTKc_Fyn; Catalytic domain of the Protein Tyrosine Kinase, Fyn
  13. XM_030244881.2XP_030100741.1  tyrosine-protein kinase Fyn isoform X1

    Conserved Domains (3) summary
    cd10418
    Location:184284
    SH2_Src_Fyn_isoform_a_like; Src homology 2 (SH2) domain found in Fyn isoform a like proteins
    cd12006
    Location:124179
    SH3_Fyn_Yrk; Src homology 3 domain of Fyn and Yrk Protein Tyrosine Kinases
    cd05070
    Location:300573
    PTKc_Fyn; Catalytic domain of the Protein Tyrosine Kinase, Fyn
  14. XM_006512539.5XP_006512602.1  tyrosine-protein kinase Fyn isoform X3

    See identical proteins and their annotated locations for XP_006512602.1

    UniProtKB/Swiss-Prot
    P39688, Q3TAT3, Q3U0T5, Q8K2A3
    Conserved Domains (3) summary
    cd10418
    Location:145245
    SH2_Src_Fyn_isoform_a_like; Src homology 2 (SH2) domain found in Fyn isoform a like proteins
    cd12006
    Location:85140
    SH3_Fyn_Yrk; Src homology 3 domain of Fyn and Yrk Protein Tyrosine Kinases
    cd05070
    Location:261534
    PTKc_Fyn; Catalytic domain of the Protein Tyrosine Kinase, Fyn
  15. XM_036155611.1XP_036011504.1  tyrosine-protein kinase Fyn isoform X4

    Related
    ENSMUSP00000117111.2, ENSMUST00000135242.8
    Conserved Domains (3) summary
    cd10368
    Location:145245
    SH2_Src_Fyn; Src homology 2 (SH2) domain found in Fyn
    cd12006
    Location:85140
    SH3_Fyn_Yrk; Src homology 3 domain of Fyn and Yrk Protein Tyrosine Kinases
    cd05070
    Location:258531
    PTKc_Fyn; Catalytic domain of the Protein Tyrosine Kinase, Fyn
  16. XM_036155605.1XP_036011498.1  tyrosine-protein kinase Fyn isoform X1

    Conserved Domains (3) summary
    cd10418
    Location:184284
    SH2_Src_Fyn_isoform_a_like; Src homology 2 (SH2) domain found in Fyn isoform a like proteins
    cd12006
    Location:124179
    SH3_Fyn_Yrk; Src homology 3 domain of Fyn and Yrk Protein Tyrosine Kinases
    cd05070
    Location:300573
    PTKc_Fyn; Catalytic domain of the Protein Tyrosine Kinase, Fyn