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ERBB2 erb-b2 receptor tyrosine kinase 2 [ Sturnus vulgaris (Common starling) ]

Gene ID: 106858712, updated on 3-Aug-2024

Summary

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Gene symbol
ERBB2
Gene description
erb-b2 receptor tyrosine kinase 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Sturnus vulgaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves; Passeriformes; Sturnidae; Sturnus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
26
Annotation release Status Assembly Chr Location
100 current Sturnus_vulgaris-1.0 (GCF_001447265.1) Unplaced Scaffold NW_014650663.1 (457779..465362)

NW_014650663.1Genomic Context describing neighboring genes Neighboring gene phenylethanolamine N-methyltransferase Neighboring gene post-GPI attachment to proteins phospholipase 3 Neighboring gene migration and invasion enhancer 1 Neighboring gene growth factor receptor bound protein 7

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_014650663.1 Unplaced Scaffold Reference Sturnus_vulgaris-1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane receptor protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in neuron differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of MAPK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in basal plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
receptor tyrosine-protein kinase erbB-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Sturnus vulgaris Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sturnus_vulgaris-1.0

Genomic

  1. NW_014650663.1 Reference Sturnus_vulgaris-1.0

    Range
    457779..465362
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_014885516.1 → XP_014741002.1  receptor tyrosine-protein kinase erbB-2

    Conserved Domains (8) summary
    cd12094
    Location:601 → 644
    TM_ErbB2; Transmembrane domain of ErbB2, a Protein Tyrosine Kinase
    smart00261
    Location:517 → 563
    FU; Furin-like repeats
    cd00064
    Location:196 → 241
    FU; Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors.
    cd05109
    Location:672 → 950
    PTKc_HER2; Catalytic domain of the Protein Tyrosine Kinase, HER2
    pfam00757
    Location:154 → 299
    Furin-like; Furin-like cysteine rich region
    pfam01030
    Location:22 → 134
    Recep_L_domain; Receptor L domain
    pfam07714
    Location:680 → 936
    Pkinase_Tyr; Protein tyrosine kinase
    pfam14843
    Location:470 → 603
    GF_recep_IV; Growth factor receptor domain IV
Nucleotide Protein
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