U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

NLRP12 NLR family pyrin domain containing 12 [ Microcebus murinus (gray mouse lemur) ]

Gene ID: 105874727, updated on 13-Mar-2024

Summary

Go to the top of the page Help
Gene symbol
NLRP12
Gene description
NLR family pyrin domain containing 12
See related
Ensembl:ENSMICG00000045956
Gene type
protein coding
RefSeq status
MODEL
Organism
Microcebus murinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes; Cheirogaleidae; Microcebus
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 22
Exon count:
7
Annotation release Status Assembly Chr Location
101 current Mmur_3.0 (GCF_000165445.2) 22 NC_033681.1 (10862155..10895636, complement)
100 previous assembly Mmur_2.0 (GCF_000165445.1) Unplaced Scaffold NW_012196397.1 (453428..487437)

Chromosome 22 - NC_033681.1Genomic Context describing neighboring genes Neighboring gene cationic amino acid transporter 3-like Neighboring gene divergent-paired related homeobox Neighboring gene uncharacterized LOC105874729 Neighboring gene uncharacterized LOC105874726 Neighboring gene myeloid associated differentiation marker Neighboring gene protein kinase C gamma

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to cytokine stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of MHC class I biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cysteine-type endopeptidase activity involved in apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
NACHT, LRR and PYD domains-containing protein 12

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Microcebus murinus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmur_3.0 Primary Assembly

Genomic

  1. NC_033681.1 Reference Mmur_3.0 Primary Assembly

    Range
    10862155..10895636 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012770854.2 → XP_012626308.1  NACHT, LRR and PYD domains-containing protein 12

    UniProtKB/TrEMBL
    A0A8B7GST6, A0A8C5Y871
    Related
    ENSMICP00000046552.1, ENSMICT00000059196.1
    Conserved Domains (6) summary
    smart00382
    Location:209 → 306
    AAA; ATPases associated with a variety of cellular activities
    cd00116
    Location:551 → 857
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:708 → 736
    LRR_RI; leucine-rich repeat [structural motif]
    pfam02758
    Location:11 → 90
    PYRIN; PAAD/DAPIN/Pyrin domain
    pfam05729
    Location:211 → 380
    NACHT; NACHT domain
    pfam14484
    Location:129 → 200
    FISNA; Fish-specific NACHT associated domain
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.