Conserved Protein Domain Family
AAA

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ATPases associated with a variety of cellular activities
AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Statistics
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PSSM-Id: 214640
View PSSM: smart00382
Aligned: 436 rows
Threshold Bit Score: 29.649
Threshold Setting Gi: 3183567
Created: 13-Jul-2011
Updated: 16-Jan-2013
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

smart00382 is classified as a model that may span more than one domain.
smart00382 is not assigned to any domain superfamily.
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3CF0_A        48 PSKGVLFYGPPGCGKTLLAKAIANECQAn----------------------FISIKGPELLt------------------ 87
gi 3023779    26 HGSLIIIEGEESTGKSVLCQRLAYGFLQnr-------------------ysVTYVSTQLTTlefikqmnslnysinkkl- 85
gi 54042814    1 MRIFITGMPGVGKTTLALKIAEKLKELGykvggfitkeirdggkrvgfkiiTLDTNEETILayvgdg------------- 67
gi 2498713    33 YPSAIYLFGHSGTGKTALTRAFLKECGKrqn-----------------vrtAHLNAIECYTtkimle------------- 82
gi 1708168    82 PFRVLLITGTAGAGKTSSIQTLAANSDc-----------------------LITATTSIAAqnlsgllnrtksaqvktif 138
gi 465325     34 RGQLVLVCAGPGTGKSAFVLAYALKSKVpt--------------------lYFSADSDAFTqlsrsvsilsgwsleratr 93
gi 133594   1165 KQKRTTVQGPPGSGKSHFAIGLAVYFSSa---------------------rVVFTACSHAAvdalcekafkflkvddc-- 1221
gi 729648    192 PSPVCLITGWAGMGKTTIALEAAYSCVDdtsvw-------------pafnsIIWVSADWKGlsfsdflnti--------- 249
gi 137606    100 CDDTCIINGKPGFGKTILALALAYKFGQk----------------------TLVICTNTSIremwaaevrkwfg------ 151
gi 130244    163 QPVIGVIYGPTGCGKSQLLRNLLSSQLItpa-----------------petVFFIAPQVDMippselkawemqicegnya 225
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3CF0_A        88 -----------------------------------MWFGESEANVR-EIFDKARQAa----------pCVLFFDE-LDSI 120
gi 3023779    86 ------------------lsgallyipvypliadnKKKDGFLKKVM-ETRAFYEK-------------DVIIFDS-ISAL 132
gi 54042814   68 -----------------------------kikvgkYAVFIENLDNVgVEAIKRALKda--------diIIIDELG-AMEF 109
gi 2498713    83 -----------------------------illdslAPDQGDALKVD-NMLDFVEQLrrqaatrvedqgFLIAVDN-AERL 131
gi 1708168   139 ktfgfnsshvsmneriscsvttldsiadqqkhdlsTYWNVIADIAE-RALNAANGKtkvip--dlcesSVIVIDE-AGVI 214
gi 465325     94 av------------reqniedavadsldeipirfnYKASPSLDEIE-NALAAYDALyed-------fpALIVVDN-ITNV 152
gi 133594   1222 -------------------trivpqrttvdcfskfKANDTGKKYIFsTINALPEVSc-----------DILLVDE-VSML 1270
gi 729648    250 --------------------------ayqlgrkeqIDKSINVKRFV-VRNALANYTre--------kpILLIVDS-IDTA 293
gi 137606    152 -----------------------fepgiigsgkynIDPPIVVSNIQ-TVNKHANNLsk--------vfGTVIVDE-VHHC 198
gi 130244    226 pgpq--------gtfipqsgtlrpkfikmayddltQEHNYDVSDPR-NVFARAAAHg----------pIAIIMDEcMENL 286
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3CF0_A       121 AKARggnigdggGAADRVINQI---------------------------------------------------------- 142
gi 3023779   133 IAND--------ASEVNVDDL----------------------------------------------------------- 145
gi 54042814  110 KSRK--------FSEVVD-------------------------------------------------------------- 119
gi 2498713   132 RDMD--------ANVLPVL------------------------------------------------------------- 142
gi 1708168   215 LRHI--------LHTVVFFYWFyn-------------------------------------------------------g 231
gi 465325    153 RTDS--------SEGDDPFSGLes-------------------------------------------------------l 169
gi 133594   1271 TNYE--------LSFINGKINYqyvvyvgdpaqlpaprtlln-------------------gslspkdynvvtnlmvcvk 1323
gi 729648    294 ERDI--------HEFITSLPQGvkvlltarenvkqtyresfgemtaiqlsgldqtdaheffqqevhhclqtcnlprkrek 365
gi 137606    199 VATT--------F------------------------------------------------------------------- 203
gi 130244    287 GGHK--------GVSKFFHAFPs--------------------------------------------------------k 302
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|.
3CF0_A       143 LTEMDGMSTKKNVFIIGATNR---PDIIDPAILRPg--RLDQLIYI-PLPD 187
gi 3023779   146 -MAFFKRITALKKIIICTVNP---KELPESVLTII---RTSATMLI-RTEL 188
gi 54042814  120 ----EVIKSDKPLLATLHRNWvnkFKDKGELYTL------TIENRE-KLFE 159
gi 2498713   143 --LRLQELTNLNLCVILLSQLp-fEKFYNKTGLSE---IVCLHLAQ-YNKA 186
gi 1708168   232 LHKTQLYKNRVIPCIVCVGS------PTQSGALISsfnPLTQNKDV-KKGF 275
gi 465325    170 MDYLHEMGRETGSCVVGLHH------VTGPHNDG------DKPIPL-SGIK 207
gi 133594   1324 PDIFLAKCYRCPKEIVDTVSTlvyDGKFIANNPES---RECFKVIV-NNGN 1370
gi 729648    366 LEQLLHLSSDLKNEFISATA-----GNPKAMALSIa-yMSDDDIPAqQLIH 410
gi 137606    204 ---------TNFLEISCARY-----KIGLSGTLKR---KDGLQVMF-KDFF 236
gi 130244    303 LHDKFPKCTGYTVLVVLHNMNp--RRDLGGNIANL---KIQSKMHI-ISPR 347
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Click on image for an interactive view with Cn3D