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CTTN cortactin [ Microcebus murinus (gray mouse lemur) ]

Gene ID: 105867508, updated on 13-Mar-2024

Summary

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Gene symbol
CTTN
Gene description
cortactin
See related
Ensembl:ENSMICG00000003767
Gene type
protein coding
RefSeq status
MODEL
Organism
Microcebus murinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes; Cheirogaleidae; Microcebus
Orthologs
human mouse all
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Genomic context

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See CTTN in Genome Data Viewer
Location:
chromosome: 5
Exon count:
21
Annotation release Status Assembly Chr Location
101 current Mmur_3.0 (GCF_000165445.2) 5 NC_033664.1 (14799304..14832174)
100 previous assembly Mmur_2.0 (GCF_000165445.1) Unplaced Scaffold NW_012204018.1 (4240130..4273000)

Chromosome 5 - NC_033664.1Genomic Context describing neighboring genes Neighboring gene Fas associated via death domain Neighboring gene PTPRF interacting protein alpha 1 Neighboring gene uncharacterized LOC105867544 Neighboring gene uncharacterized LOC105867439 Neighboring gene SH3 and multiple ankyrin repeat domains 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables actin filament binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of actin filament polymerization IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in actin filament IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cortical actin cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in focal adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in lamellipodium IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in site of polarized growth IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
src substrate cortactin

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Microcebus murinus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmur_3.0 Primary Assembly

Genomic

  1. NC_033664.1 Reference Mmur_3.0 Primary Assembly

    Range
    14799304..14832174
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012757658.1 → XP_012613112.1  src substrate cortactin isoform X2

    UniProtKB/TrEMBL
    A0A8C5VQ75
    Related
    ENSMICP00000024933.1, ENSMICT00000050544.2
    Conserved Domains (3) summary
    cd11959
    Location:498 → 550
    SH3_Cortactin; Src homology 3 domain of Cortactin
    pfam02218
    Location:231 → 266
    HS1_rep; Repeat in HS1/Cortactin
    cl05005
    Location:336 → 399
    TAF4; TATA Binding Protein (TBP) Associated Factor 4 (TAF4) is one of several TAFs that bind TBP and is involved in forming Transcription Factor IID (TFIID) complex

  2. XM_012757654.1 → XP_012613108.1  src substrate cortactin isoform X1

    See identical proteins and their annotated locations for XP_012613108.1

    UniProtKB/TrEMBL
    A0A8B7FW20
    Conserved Domains (3) summary
    cd11959
    Location:503 → 555
    SH3_Cortactin; Src homology 3 domain of Cortactin
    pfam02218
    Location:157 → 192
    HS1_rep; Repeat in HS1/Cortactin
    cl05005
    Location:341 → 404
    TAF4; TATA Binding Protein (TBP) Associated Factor 4 (TAF4) is one of several TAFs that bind TBP and is involved in forming Transcription Factor IID (TFIID) complex

  3. XM_012757660.1 → XP_012613114.1  src substrate cortactin isoform X3

    UniProtKB/TrEMBL
    A0A8B7FV89
    Related
    ENSMICP00000033372.1, ENSMICT00000035843.2
    Conserved Domains (3) summary
    cd11959
    Location:461 → 513
    SH3_Cortactin; Src homology 3 domain of Cortactin
    pfam02218
    Location:231 → 266
    HS1_rep; Repeat in HS1/Cortactin
    cl05005
    Location:299 → 362
    TAF4; TATA Binding Protein (TBP) Associated Factor 4 (TAF4) is one of several TAFs that bind TBP and is involved in forming Transcription Factor IID (TFIID) complex

  4. XM_012757661.1 → XP_012613115.1  src substrate cortactin isoform X4

    UniProtKB/TrEMBL
    A0A8B7FW23
    Related
    ENSMICP00000048055.1, ENSMICT00000063120.1
    Conserved Domains (3) summary
    cd11959
    Location:424 → 476
    SH3_Cortactin; Src homology 3 domain of Cortactin
    pfam02218
    Location:157 → 192
    HS1_rep; Repeat in HS1/Cortactin
    cl05005
    Location:262 → 325
    TAF4; TATA Binding Protein (TBP) Associated Factor 4 (TAF4) is one of several TAFs that bind TBP and is involved in forming Transcription Factor IID (TFIID) complex

  5. XM_012757656.2 → XP_012613110.1  src substrate cortactin isoform X1

    See identical proteins and their annotated locations for XP_012613110.1

    UniProtKB/TrEMBL
    A0A8B7FW20
    Conserved Domains (3) summary
    cd11959
    Location:503 → 555
    SH3_Cortactin; Src homology 3 domain of Cortactin
    pfam02218
    Location:157 → 192
    HS1_rep; Repeat in HS1/Cortactin
    cl05005
    Location:341 → 404
    TAF4; TATA Binding Protein (TBP) Associated Factor 4 (TAF4) is one of several TAFs that bind TBP and is involved in forming Transcription Factor IID (TFIID) complex

  6. XM_012757655.2 → XP_012613109.1  src substrate cortactin isoform X1

    See identical proteins and their annotated locations for XP_012613109.1

    UniProtKB/TrEMBL
    A0A8B7FW20
    Conserved Domains (3) summary
    cd11959
    Location:503 → 555
    SH3_Cortactin; Src homology 3 domain of Cortactin
    pfam02218
    Location:157 → 192
    HS1_rep; Repeat in HS1/Cortactin
    cl05005
    Location:341 → 404
    TAF4; TATA Binding Protein (TBP) Associated Factor 4 (TAF4) is one of several TAFs that bind TBP and is involved in forming Transcription Factor IID (TFIID) complex

  7. XM_012757657.1 → XP_012613111.1  src substrate cortactin isoform X1

    See identical proteins and their annotated locations for XP_012613111.1

    UniProtKB/TrEMBL
    A0A8B7FW20
    Conserved Domains (3) summary
    cd11959
    Location:503 → 555
    SH3_Cortactin; Src homology 3 domain of Cortactin
    pfam02218
    Location:157 → 192
    HS1_rep; Repeat in HS1/Cortactin
    cl05005
    Location:341 → 404
    TAF4; TATA Binding Protein (TBP) Associated Factor 4 (TAF4) is one of several TAFs that bind TBP and is involved in forming Transcription Factor IID (TFIID) complex
Nucleotide Protein
Heading Accession and Version

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