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DDR1 discoidin domain receptor tyrosine kinase 1 [ Cercocebus atys (sooty mangabey) ]

Gene ID: 105600018, updated on 11-Apr-2024

Summary

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Gene symbol
DDR1
Gene description
discoidin domain receptor tyrosine kinase 1
See related
Ensembl:ENSCATG00000035224
Gene type
protein coding
RefSeq status
MODEL
Organism
Cercocebus atys
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Cercocebus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
24
Annotation release Status Assembly Chr Location
100 current Caty_1.0 (GCF_000955945.1) Unplaced Scaffold NW_012002513.1 (387562..406902, complement)

NW_012002513.1Genomic Context describing neighboring genes Neighboring gene valyl-tRNA synthetase 2, mitochondrial Neighboring gene general transcription factor IIH subunit 4 Neighboring gene flotillin 1 Neighboring gene immediate early response 3

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012002513.1 Unplaced Scaffold Reference Caty_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables collagen binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein tyrosine kinase collagen receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
epithelial discoidin domain-containing receptor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cercocebus atys Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Caty_1.0

Genomic

  1. NW_012002513.1 Reference Caty_1.0

    Range
    387562..406902 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012090744.1 → XP_011946134.1  epithelial discoidin domain-containing receptor 1 isoform X2

    See identical proteins and their annotated locations for XP_011946134.1

    UniProtKB/TrEMBL
    A0A2K5ME34
    Conserved Domains (4) summary
    cd05096
    Location:604 → 907
    PTKc_DDR1; Catalytic domain of the Protein Tyrosine Kinase, Discoidin Domain Receptor 1
    smart00221
    Location:610 → 905
    STYKc; Protein kinase; unclassified specificity
    smart00231
    Location:30 → 185
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain
    cd00057
    Location:60 → 184
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.

  2. XM_012090740.1 → XP_011946130.1  epithelial discoidin domain-containing receptor 1 isoform X2

    See identical proteins and their annotated locations for XP_011946130.1

    UniProtKB/TrEMBL
    A0A2K5ME34
    Conserved Domains (4) summary
    cd05096
    Location:604 → 907
    PTKc_DDR1; Catalytic domain of the Protein Tyrosine Kinase, Discoidin Domain Receptor 1
    smart00221
    Location:610 → 905
    STYKc; Protein kinase; unclassified specificity
    smart00231
    Location:30 → 185
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain
    cd00057
    Location:60 → 184
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.

  3. XM_012090741.1 → XP_011946131.1  epithelial discoidin domain-containing receptor 1 isoform X2

    See identical proteins and their annotated locations for XP_011946131.1

    UniProtKB/TrEMBL
    A0A2K5ME34
    Conserved Domains (4) summary
    cd05096
    Location:604 → 907
    PTKc_DDR1; Catalytic domain of the Protein Tyrosine Kinase, Discoidin Domain Receptor 1
    smart00221
    Location:610 → 905
    STYKc; Protein kinase; unclassified specificity
    smart00231
    Location:30 → 185
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain
    cd00057
    Location:60 → 184
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.

  4. XM_012090735.1 → XP_011946125.1  epithelial discoidin domain-containing receptor 1 isoform X1

    See identical proteins and their annotated locations for XP_011946125.1

    UniProtKB/TrEMBL
    A0A2K5ME34
    Conserved Domains (4) summary
    cd05096
    Location:630 → 933
    PTKc_DDR1; Catalytic domain of the Protein Tyrosine Kinase, Discoidin Domain Receptor 1
    smart00221
    Location:636 → 931
    STYKc; Protein kinase; unclassified specificity
    smart00231
    Location:56 → 211
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain
    cd00057
    Location:86 → 210
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.

  5. XM_012090751.1 → XP_011946141.1  epithelial discoidin domain-containing receptor 1 isoform X4

    See identical proteins and their annotated locations for XP_011946141.1

    UniProtKB/TrEMBL
    A0A2K5ME23, A0A2K5ME31
    Related
    ENSCATP00000023444.1, ENSCATT00000047661.1
    Conserved Domains (4) summary
    cd05096
    Location:567 → 870
    PTKc_DDR1; Catalytic domain of the Protein Tyrosine Kinase, Discoidin Domain Receptor 1
    smart00221
    Location:573 → 868
    STYKc; Protein kinase; unclassified specificity
    smart00231
    Location:30 → 185
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain
    cd00057
    Location:60 → 184
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.

  6. XM_012090742.1 → XP_011946132.1  epithelial discoidin domain-containing receptor 1 isoform X2

    See identical proteins and their annotated locations for XP_011946132.1

    UniProtKB/TrEMBL
    A0A2K5ME34
    Conserved Domains (4) summary
    cd05096
    Location:604 → 907
    PTKc_DDR1; Catalytic domain of the Protein Tyrosine Kinase, Discoidin Domain Receptor 1
    smart00221
    Location:610 → 905
    STYKc; Protein kinase; unclassified specificity
    smart00231
    Location:30 → 185
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain
    cd00057
    Location:60 → 184
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.

  7. XM_012090747.1 → XP_011946137.1  epithelial discoidin domain-containing receptor 1 isoform X2

    See identical proteins and their annotated locations for XP_011946137.1

    UniProtKB/TrEMBL
    A0A2K5ME34
    Related
    ENSCATP00000023462.1, ENSCATT00000047679.1
    Conserved Domains (4) summary
    cd05096
    Location:604 → 907
    PTKc_DDR1; Catalytic domain of the Protein Tyrosine Kinase, Discoidin Domain Receptor 1
    smart00221
    Location:610 → 905
    STYKc; Protein kinase; unclassified specificity
    smart00231
    Location:30 → 185
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain
    cd00057
    Location:60 → 184
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.

  8. XM_012090734.1 → XP_011946124.1  epithelial discoidin domain-containing receptor 1 isoform X1

    See identical proteins and their annotated locations for XP_011946124.1

    UniProtKB/TrEMBL
    A0A2K5ME34
    Related
    ENSCATP00000023422.1, ENSCATT00000047639.1
    Conserved Domains (4) summary
    cd05096
    Location:630 → 933
    PTKc_DDR1; Catalytic domain of the Protein Tyrosine Kinase, Discoidin Domain Receptor 1
    smart00221
    Location:636 → 931
    STYKc; Protein kinase; unclassified specificity
    smart00231
    Location:56 → 211
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain
    cd00057
    Location:86 → 210
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.

  9. XM_012090739.1 → XP_011946129.1  epithelial discoidin domain-containing receptor 1 isoform X2

    See identical proteins and their annotated locations for XP_011946129.1

    UniProtKB/TrEMBL
    A0A2K5ME34
    Conserved Domains (4) summary
    cd05096
    Location:604 → 907
    PTKc_DDR1; Catalytic domain of the Protein Tyrosine Kinase, Discoidin Domain Receptor 1
    smart00221
    Location:610 → 905
    STYKc; Protein kinase; unclassified specificity
    smart00231
    Location:30 → 185
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain
    cd00057
    Location:60 → 184
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.

  10. XM_012090749.1 → XP_011946139.1  epithelial discoidin domain-containing receptor 1 isoform X4

    See identical proteins and their annotated locations for XP_011946139.1

    UniProtKB/TrEMBL
    A0A2K5ME23, A0A2K5ME31
    Conserved Domains (4) summary
    cd05096
    Location:567 → 870
    PTKc_DDR1; Catalytic domain of the Protein Tyrosine Kinase, Discoidin Domain Receptor 1
    smart00221
    Location:573 → 868
    STYKc; Protein kinase; unclassified specificity
    smart00231
    Location:30 → 185
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain
    cd00057
    Location:60 → 184
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.

  11. XM_012090737.1 → XP_011946127.1  epithelial discoidin domain-containing receptor 1 isoform X2

    See identical proteins and their annotated locations for XP_011946127.1

    UniProtKB/TrEMBL
    A0A2K5ME34
    Conserved Domains (4) summary
    cd05096
    Location:604 → 907
    PTKc_DDR1; Catalytic domain of the Protein Tyrosine Kinase, Discoidin Domain Receptor 1
    smart00221
    Location:610 → 905
    STYKc; Protein kinase; unclassified specificity
    smart00231
    Location:30 → 185
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain
    cd00057
    Location:60 → 184
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.

  12. XM_012090750.1 → XP_011946140.1  epithelial discoidin domain-containing receptor 1 isoform X4

    See identical proteins and their annotated locations for XP_011946140.1

    UniProtKB/TrEMBL
    A0A2K5ME23, A0A2K5ME31
    Related
    ENSCATP00000023434.1, ENSCATT00000047651.1
    Conserved Domains (4) summary
    cd05096
    Location:567 → 870
    PTKc_DDR1; Catalytic domain of the Protein Tyrosine Kinase, Discoidin Domain Receptor 1
    smart00221
    Location:573 → 868
    STYKc; Protein kinase; unclassified specificity
    smart00231
    Location:30 → 185
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain
    cd00057
    Location:60 → 184
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.

  13. XM_012090738.1 → XP_011946128.1  epithelial discoidin domain-containing receptor 1 isoform X2

    See identical proteins and their annotated locations for XP_011946128.1

    UniProtKB/TrEMBL
    A0A2K5ME34
    Conserved Domains (4) summary
    cd05096
    Location:604 → 907
    PTKc_DDR1; Catalytic domain of the Protein Tyrosine Kinase, Discoidin Domain Receptor 1
    smart00221
    Location:610 → 905
    STYKc; Protein kinase; unclassified specificity
    smart00231
    Location:30 → 185
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain
    cd00057
    Location:60 → 184
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.

  14. XM_012090748.1 → XP_011946138.1  epithelial discoidin domain-containing receptor 1 isoform X3

    UniProtKB/TrEMBL
    A0A2K5ME31
    Conserved Domains (4) summary
    cd05096
    Location:593 → 896
    PTKc_DDR1; Catalytic domain of the Protein Tyrosine Kinase, Discoidin Domain Receptor 1
    smart00221
    Location:599 → 894
    STYKc; Protein kinase; unclassified specificity
    smart00231
    Location:56 → 211
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain
    cd00057
    Location:86 → 210
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.

  15. XM_012090743.1 → XP_011946133.1  epithelial discoidin domain-containing receptor 1 isoform X2

    See identical proteins and their annotated locations for XP_011946133.1

    UniProtKB/TrEMBL
    A0A2K5ME34
    Conserved Domains (4) summary
    cd05096
    Location:604 → 907
    PTKc_DDR1; Catalytic domain of the Protein Tyrosine Kinase, Discoidin Domain Receptor 1
    smart00221
    Location:610 → 905
    STYKc; Protein kinase; unclassified specificity
    smart00231
    Location:30 → 185
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain
    cd00057
    Location:60 → 184
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.

  16. XM_012090736.1 → XP_011946126.1  epithelial discoidin domain-containing receptor 1 isoform X1

    See identical proteins and their annotated locations for XP_011946126.1

    UniProtKB/TrEMBL
    A0A2K5ME34
    Conserved Domains (4) summary
    cd05096
    Location:630 → 933
    PTKc_DDR1; Catalytic domain of the Protein Tyrosine Kinase, Discoidin Domain Receptor 1
    smart00221
    Location:636 → 931
    STYKc; Protein kinase; unclassified specificity
    smart00231
    Location:56 → 211
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain
    cd00057
    Location:86 → 210
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.

  17. XM_012090746.1 → XP_011946136.1  epithelial discoidin domain-containing receptor 1 isoform X2

    See identical proteins and their annotated locations for XP_011946136.1

    UniProtKB/TrEMBL
    A0A2K5ME34
    Conserved Domains (4) summary
    cd05096
    Location:604 → 907
    PTKc_DDR1; Catalytic domain of the Protein Tyrosine Kinase, Discoidin Domain Receptor 1
    smart00221
    Location:610 → 905
    STYKc; Protein kinase; unclassified specificity
    smart00231
    Location:30 → 185
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain
    cd00057
    Location:60 → 184
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.

  18. XM_012090752.1 → XP_011946142.1  epithelial discoidin domain-containing receptor 1 isoform X5

    Conserved Domains (2) summary
    smart00231
    Location:56 → 211
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain
    cd00057
    Location:86 → 210
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.
Nucleotide Protein
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