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TEK TEK receptor tyrosine kinase [ Mandrillus leucophaeus (drill) ]

Gene ID: 105549728, updated on 11-Apr-2024

Summary

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Gene symbol
TEK
Gene description
TEK receptor tyrosine kinase
See related
Ensembl:ENSMLEG00000038804
Gene type
protein coding
RefSeq status
MODEL
Organism
Mandrillus leucophaeus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Mandrillus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
23
Annotation release Status Assembly Chr Location
100 current Mleu.le_1.0 (GCF_000951045.1) Unplaced Scaffold NW_012104854.1 (1936267..2078907)

NW_012104854.1Genomic Context describing neighboring genes Neighboring gene phospholipase A2 activating protein Neighboring gene melanoma-associated antigen 3-like Neighboring gene intraflagellar transport 74 Neighboring gene equatorin Neighboring gene MOB kinase activator 3B Neighboring gene interferon kappa

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012104854.1 Unplaced Scaffold Reference Mleu.le_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane receptor protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in angiogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in endothelial cell proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of MAPK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of endothelial cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
angiopoietin-1 receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Mandrillus leucophaeus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mleu.le_1.0

Genomic

  1. NW_012104854.1 Reference Mleu.le_1.0

    Range
    1936267..2078907
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011994372.1 → XP_011849762.1  angiopoietin-1 receptor isoform X1

    UniProtKB/TrEMBL
    A0A2K5ZN87, A0A2K5ZNA1
    Related
    ENSMLEP00000029281.1, ENSMLET00000052836.1
    Conserved Domains (5) summary
    cd05088
    Location:816 → 1118
    PTKc_Tie2; Catalytic domain of the Protein Tyrosine Kinase, Tie2
    smart00221
    Location:824 → 1092
    STYKc; Protein kinase; unclassified specificity
    cd00063
    Location:639 → 731
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00041
    Location:544 → 626
    fn3; Fibronectin type III domain
    pfam10430
    Location:24 → 118
    Ig_Tie2_1; Tie-2 Ig-like domain 1

  2. XM_011994374.1 → XP_011849764.1  angiopoietin-1 receptor isoform X2

    UniProtKB/TrEMBL
    A0A2K5ZNA1, A0A2K5ZNC5
    Related
    ENSMLEP00000029283.1, ENSMLET00000052838.1
    Conserved Domains (6) summary
    cd05088
    Location:773 → 1075
    PTKc_Tie2; Catalytic domain of the Protein Tyrosine Kinase, Tie2
    smart00221
    Location:781 → 1049
    STYKc; Protein kinase; unclassified specificity
    cd00055
    Location:230 → 275
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00063
    Location:596 → 688
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00041
    Location:501 → 583
    fn3; Fibronectin type III domain
    pfam10430
    Location:24 → 118
    Ig_Tie2_1; Tie-2 Ig-like domain 1

  3. XM_011994375.1 → XP_011849765.1  angiopoietin-1 receptor isoform X3

    UniProtKB/TrEMBL
    A0A2K5ZNA1, A0A2K5ZNC4
    Related
    ENSMLEP00000029289.1, ENSMLET00000052844.1
    Conserved Domains (5) summary
    cd05088
    Location:668 → 970
    PTKc_Tie2; Catalytic domain of the Protein Tyrosine Kinase, Tie2
    smart00221
    Location:676 → 944
    STYKc; Protein kinase; unclassified specificity
    cd00055
    Location:126 → 171
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00063
    Location:492 → 584
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00041
    Location:397 → 479
    fn3; Fibronectin type III domain
Nucleotide Protein
Heading Accession and Version

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