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INPP5B inositol polyphosphate-5-phosphatase B [ Pteropus vampyrus (large flying fox) ]

Gene ID: 105306390, updated on 30-Mar-2024

Summary

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Gene symbol
INPP5B
Gene description
inositol polyphosphate-5-phosphatase B
Gene type
protein coding
RefSeq status
MODEL
Organism
Pteropus vampyrus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yinpterochiroptera; Pteropodoidea; Pteropodidae; Pteropodinae; Pteropus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
26
Annotation release Status Assembly Chr Location
101 current Pvam_2.0 (GCF_000151845.1) Unplaced Scaffold NW_011889216.1 (1145356..1189310)

NW_011889216.1Genomic Context describing neighboring genes Neighboring gene splicing factor 3a subunit 3 Neighboring gene uncharacterized LOC111732224 Neighboring gene metal regulatory transcription factor 1 Neighboring gene chromosome unknown C1orf122 homolog Neighboring gene yrdC N6-threonylcarbamoyltransferase domain containing

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_011889216 Unplaced Scaffold Reference Pvam_2.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables inositol-1,4,5-trisphosphate 5-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in phosphatidylinositol dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
type II inositol 1,4,5-trisphosphate 5-phosphatase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Pteropus vampyrus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Pvam_2.0

Genomic

  1. NW_011889216.1 Reference Pvam_2.0

    Range
    1145356..1189310
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011381347.2 → XP_011379649.1  type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X1

    UniProtKB/TrEMBL
    A0A6P3RFV2
    Conserved Domains (3) summary
    cd09093
    Location:262 → 555
    INPP5c_INPP5B; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of Type II inositol polyphosphate 5-phosphatase I, Oculocerebrorenal syndrome of Lowe 1, and related proteins
    cd04380
    Location:689 → 904
    RhoGAP_OCRL1; RhoGAP_OCRL1: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in OCRL1-like proteins. OCRL1 (oculocerebrorenal syndrome of Lowe 1)-like proteins contain two conserved domains: a central inositol polyphosphate ...
    pfam16776
    Location:6 → 149
    INPP5B_PH; Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain

  2. XM_011381348.2 → XP_011379650.1  type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X2

    UniProtKB/TrEMBL
    A0A6P3RU24
    Conserved Domains (3) summary
    cd09093
    Location:218 → 511
    INPP5c_INPP5B; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of Type II inositol polyphosphate 5-phosphatase I, Oculocerebrorenal syndrome of Lowe 1, and related proteins
    cd04380
    Location:645 → 860
    RhoGAP_OCRL1; RhoGAP_OCRL1: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in OCRL1-like proteins. OCRL1 (oculocerebrorenal syndrome of Lowe 1)-like proteins contain two conserved domains: a central inositol polyphosphate ...
    pfam16776
    Location:6 → 131
    INPP5B_PH; Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain

  3. XM_011381351.2 → XP_011379653.1  type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X5

    UniProtKB/TrEMBL
    A0A6P3RDJ9
    Conserved Domains (3) summary
    cd09093
    Location:262 → 555
    INPP5c_INPP5B; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of Type II inositol polyphosphate 5-phosphatase I, Oculocerebrorenal syndrome of Lowe 1, and related proteins
    pfam16776
    Location:6 → 149
    INPP5B_PH; Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain
    cl02570
    Location:689 → 788
    RhoGAP; RhoGAP: GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when ...

  4. XM_011381352.2 → XP_011379654.1  type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X6

    UniProtKB/TrEMBL
    A0A6P3RFV8
    Conserved Domains (3) summary
    cd09093
    Location:262 → 555
    INPP5c_INPP5B; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of Type II inositol polyphosphate 5-phosphatase I, Oculocerebrorenal syndrome of Lowe 1, and related proteins
    pfam16776
    Location:6 → 149
    INPP5B_PH; Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain
    cl02570
    Location:689 → 788
    RhoGAP; RhoGAP: GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when ...

  5. XM_011381349.2 → XP_011379651.1  type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X3

    UniProtKB/TrEMBL
    A0A6P3RM28
    Conserved Domains (3) summary
    cd09093
    Location:203 → 496
    INPP5c_INPP5B; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of Type II inositol polyphosphate 5-phosphatase I, Oculocerebrorenal syndrome of Lowe 1, and related proteins
    cd04380
    Location:630 → 845
    RhoGAP_OCRL1; RhoGAP_OCRL1: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in OCRL1-like proteins. OCRL1 (oculocerebrorenal syndrome of Lowe 1)-like proteins contain two conserved domains: a central inositol polyphosphate ...
    cl17171
    Location:1 → 90
    PH-like; Pleckstrin homology-like domain

  6. XM_011381350.2 → XP_011379652.1  type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X4

    UniProtKB/TrEMBL
    A0A6P6BX99
    Conserved Domains (3) summary
    cd09093
    Location:180 → 473
    INPP5c_INPP5B; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of Type II inositol polyphosphate 5-phosphatase I, Oculocerebrorenal syndrome of Lowe 1, and related proteins
    cd04380
    Location:607 → 822
    RhoGAP_OCRL1; RhoGAP_OCRL1: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in OCRL1-like proteins. OCRL1 (oculocerebrorenal syndrome of Lowe 1)-like proteins contain two conserved domains: a central inositol polyphosphate ...
    cl17171
    Location:4 → 67
    PH-like; Pleckstrin homology-like domain

  7. XM_023523993.1 → XP_023379761.1  type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X4

    UniProtKB/TrEMBL
    A0A6P6BX99
    Conserved Domains (3) summary
    cd09093
    Location:180 → 473
    INPP5c_INPP5B; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of Type II inositol polyphosphate 5-phosphatase I, Oculocerebrorenal syndrome of Lowe 1, and related proteins
    cd04380
    Location:607 → 822
    RhoGAP_OCRL1; RhoGAP_OCRL1: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in OCRL1-like proteins. OCRL1 (oculocerebrorenal syndrome of Lowe 1)-like proteins contain two conserved domains: a central inositol polyphosphate ...
    cl17171
    Location:4 → 67
    PH-like; Pleckstrin homology-like domain

  8. XM_023523994.1 → XP_023379762.1  type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X8

    UniProtKB/TrEMBL
    A0A6P6BXA8
    Conserved Domains (2) summary
    cd09093
    Location:45 → 338
    INPP5c_INPP5B; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of Type II inositol polyphosphate 5-phosphatase I, Oculocerebrorenal syndrome of Lowe 1, and related proteins
    cd04380
    Location:472 → 687
    RhoGAP_OCRL1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in OCRL1-like proteins. OCRL1 (oculocerebrorenal syndrome of Lowe 1)-like proteins contain two conserved domains: a central inositol polyphosphate 5-phosphatase domain and ...

  9. XM_023523992.1 → XP_023379760.1  type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X7

    UniProtKB/TrEMBL
    A0A6P6BXZ2
    Conserved Domains (2) summary
    cd09093
    Location:101 → 394
    INPP5c_INPP5B; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of Type II inositol polyphosphate 5-phosphatase I, Oculocerebrorenal syndrome of Lowe 1, and related proteins
    cd04380
    Location:528 → 743
    RhoGAP_OCRL1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in OCRL1-like proteins. OCRL1 (oculocerebrorenal syndrome of Lowe 1)-like proteins contain two conserved domains: a central inositol polyphosphate 5-phosphatase domain and ...
Nucleotide Protein
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