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NCOA2 nuclear receptor coactivator 2 [ Pteropus vampyrus (large flying fox) ]

Gene ID: 105295104, updated on 30-Mar-2024

Summary

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Gene symbol
NCOA2
Gene description
nuclear receptor coactivator 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Pteropus vampyrus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yinpterochiroptera; Pteropodoidea; Pteropodidae; Pteropodinae; Pteropus
Orthologs
human mouse all
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Genomic context

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See NCOA2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
19
Annotation release Status Assembly Chr Location
101 current Pvam_2.0 (GCF_000151845.1) Unplaced Scaffold NW_011888880.1 (5414480..5577994, complement)

NW_011888880.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC111742691 Neighboring gene tigger transposable element-derived protein 1-like Neighboring gene 5S ribosomal RNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_011888880 Unplaced Scaffold Reference Pvam_2.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables nuclear receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nuclear receptor coactivator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to hormone stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
nuclear receptor coactivator 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Pteropus vampyrus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Pvam_2.0

Genomic

  1. NW_011888880.1 Reference Pvam_2.0

    Range
    5414480..5577994 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023533293.1 → XP_023389061.1  nuclear receptor coactivator 2

    UniProtKB/TrEMBL
    A0A6P6CNF9
    Conserved Domains (9) summary
    smart00353
    Location:35 → 88
    HLH; helix loop helix domain
    cd00130
    Location:123 → 213
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam07469
    Location:1276 → 1333
    DUF1518; Domain of unknown function (DUF1518)
    pfam08815
    Location:1066 → 1111
    Nuc_rec_co-act; Nuclear receptor coactivator
    pfam08832
    Location:636 → 705
    SRC-1; Steroid receptor coactivator
    pfam09606
    Location:917 → 1355
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam14598
    Location:268 → 378
    PAS_11; PAS domain
    pfam16279
    Location:727 → 812
    DUF4927; Domain of unknown function (DUF4927)
    pfam16665
    Location:459 → 583
    NCOA_u2; Unstructured region on nuclear receptor coactivator protein
Nucleotide Protein
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