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SRC SRC proto-oncogene, non-receptor tyrosine kinase [ Camelus dromedarius (Arabian camel) ]

Gene ID: 105084996, updated on 6-Jun-2024

Summary

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Gene symbol
SRC
Gene description
SRC proto-oncogene, non-receptor tyrosine kinase
Locus tag
Cadr_000021173
Gene type
protein coding
RefSeq status
MODEL
Organism
Camelus dromedarius
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Tylopoda; Camelidae; Camelus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 18
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2024_04 current mCamDro1.pat (GCF_036321535.1) 18 NC_087453.1 (17895604..17946057, complement)
101 previous assembly CamDro3 (GCF_000803125.2) 19 NC_044529.1 (19305015..19357823, complement)

Chromosome 18 - NC_087453.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105084999 Neighboring gene BLCAP apoptosis inducing factor Neighboring gene neuronatin Neighboring gene mannosidase beta like Neighboring gene growth hormone releasing hormone

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables non-membrane spanning protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in bone resorption IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in epidermal growth factor receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in innate immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of extrinsic apoptotic signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of intrinsic apoptotic signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in osteoclast development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in progesterone receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extrinsic component of cytoplasmic side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
proto-oncogene tyrosine-protein kinase Src
Names
Neuronal proto-oncogene tyrosine-protein kinase Src

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036321535.1-RS_2024_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mCamDro1.pat

Genomic

  1. NC_087453.1 Reference mCamDro1.pat

    Range
    17895604..17946057 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_064475707.1 → XP_064331777.1  proto-oncogene tyrosine-protein kinase Src isoform X1

    UniProtKB/TrEMBL
    A0A5N4CUW3

  2. XM_064475705.1 → XP_064331775.1  proto-oncogene tyrosine-protein kinase Src isoform X1

    UniProtKB/TrEMBL
    A0A5N4CUW3

  3. XM_031433845.2 → XP_031289705.1  proto-oncogene tyrosine-protein kinase Src isoform X2

    Conserved Domains (3) summary
    cd10365
    Location:147 → 247
    SH2_Src_Src; Src homology 2 (SH2) domain found in tyrosine kinase sarcoma (Src)
    cd12008
    Location:88 → 143
    SH3_Src; Src homology 3 domain of Src Protein Tyrosine Kinase
    cd05071
    Location:260 → 536
    PTKc_Src; Catalytic domain of the Protein Tyrosine Kinase, Src

  4. XM_031433844.2 → XP_031289704.1  proto-oncogene tyrosine-protein kinase Src isoform X1

    UniProtKB/TrEMBL
    A0A5N4CUW3
    Conserved Domains (3) summary
    cd10365
    Location:153 → 253
    SH2_Src_Src; Src homology 2 (SH2) domain found in tyrosine kinase sarcoma (Src)
    cd12008
    Location:88 → 149
    SH3_Src; Src homology 3 domain of Src Protein Tyrosine Kinase
    cd05071
    Location:266 → 542
    PTKc_Src; Catalytic domain of the Protein Tyrosine Kinase, Src

  5. XM_064475706.1 → XP_064331776.1  proto-oncogene tyrosine-protein kinase Src isoform X1

    UniProtKB/TrEMBL
    A0A5N4CUW3

  6. XM_064475708.1 → XP_064331778.1  proto-oncogene tyrosine-protein kinase Src isoform X1

    UniProtKB/TrEMBL
    A0A5N4CUW3

  7. XM_064475702.1 → XP_064331772.1  proto-oncogene tyrosine-protein kinase Src isoform X1

    UniProtKB/TrEMBL
    A0A5N4CUW3

  8. XM_064475703.1 → XP_064331773.1  proto-oncogene tyrosine-protein kinase Src isoform X1

    UniProtKB/TrEMBL
    A0A5N4CUW3

  9. XM_064475709.1 → XP_064331779.1  proto-oncogene tyrosine-protein kinase Src isoform X3

Nucleotide Protein
Heading Accession and Version

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