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APLP2 amyloid beta precursor like protein 2 [ Bison bison bison ]

Gene ID: 104991999, updated on 12-Mar-2024

Summary

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Gene symbol
APLP2
Gene description
amyloid beta precursor like protein 2
See related
Ensembl:ENSBBBG00000015615
Gene type
protein coding
RefSeq status
MODEL
Organism
Bison bison bison (sub-species: bison)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bison
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
16
Annotation release Status Assembly Chr Location
100 current Bison_UMD1.0 (GCF_000754665.1) Unplaced Scaffold NW_011494777.1 (5773900..5803027)

NW_011494777.1Genomic Context describing neighboring genes Neighboring gene PR/SET domain 10 Neighboring gene caspase-3 pseudogene Neighboring gene zinc finger protein 740 pseudogene Neighboring gene ST14 transmembrane serine protease matriptase Neighboring gene zinc finger and BTB domain containing 44

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_011494777.1 Unplaced Scaffold Reference Bison_UMD1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables heparin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables serine-type endopeptidase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transition metal ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in axonogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in central nervous system development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
amyloid-like protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Bison bison bison Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Bison_UMD1.0 Primary Assembly

Genomic

  1. NW_011494777.1 Reference Bison_UMD1.0 Primary Assembly

    Range
    5773900..5803027
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010844704.1 → XP_010843006.1  amyloid-like protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A6P3HKT6
    Related
    ENSBBBP00000021825.1, ENSBBBT00000002519.1
    Conserved Domains (5) summary
    smart00006
    Location:1 → 151
    A4_EXTRA; amyloid A4
    pfam02177
    Location:1 → 94
    APP_N; Amyloid A4 N-terminal heparin-binding
    pfam10515
    Location:592 → 642
    APP_amyloid; beta-amyloid precursor protein C-terminus
    pfam12924
    Location:96 → 151
    APP_Cu_bd; Copper-binding of amyloid precursor, CuBD
    pfam12925
    Location:260 → 442
    APP_E2; E2 domain of amyloid precursor protein

  2. XM_010844703.1 → XP_010843005.1  amyloid-like protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A6P3HWV1
    Related
    ENSBBBP00000021839.1, ENSBBBT00000002517.1
    Conserved Domains (6) summary
    smart00006
    Location:1 → 151
    A4_EXTRA; amyloid A4
    pfam00014
    Location:260 → 312
    Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
    pfam02177
    Location:1 → 94
    APP_N; Amyloid A4 N-terminal heparin-binding
    pfam10515
    Location:648 → 698
    APP_amyloid; beta-amyloid precursor protein C-terminus
    pfam12924
    Location:96 → 151
    APP_Cu_bd; Copper-binding of amyloid precursor, CuBD
    pfam12925
    Location:316 → 498
    APP_E2; E2 domain of amyloid precursor protein
Nucleotide Protein
Heading Accession and Version

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