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Adam10 ADAM metallopeptidase domain 10 [ Fukomys damarensis (Damara mole-rat) ]

Gene ID: 104874232, updated on 12-Mar-2024

Summary

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Gene symbol
Adam10
Gene description
ADAM metallopeptidase domain 10
Locus tag
H920_12604
See related
Ensembl:ENSFDAG00000016016
Gene type
protein coding
RefSeq status
MODEL
Organism
Fukomys damarensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Fukomys
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
15
Annotation release Status Assembly Chr Location
102 current DMR_v1.0_HiC (GCF_012274545.1) Unplaced Scaffold NW_022900937.1 (11430939..11538956, complement)
101 previous assembly DMR_v1.0 (GCF_000743615.1) Unplaced Scaffold NW_011045877.1 (5623928..5766890)

NW_022900937.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC104874235 Neighboring gene uncharacterized LOC109118586 Neighboring gene lipase C, hepatic type Neighboring gene U6 spliceosomal RNA Neighboring gene small EDRK-rich factor 1-like Neighboring gene uncharacterized LOC104874233

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metalloendopeptidase activity involved in amyloid precursor protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Notch signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in membrane protein ectodomain proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in synaptic membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
disintegrin and metalloproteinase domain-containing protein 10
Names
Disintegrin and metalloproteinase domain-containing protein 10

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Fukomys damarensis Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference DMR_v1.0_HiC Primary Assembly

Genomic

  1. NW_022900937.1 Reference DMR_v1.0_HiC Primary Assembly

    Range
    11430939..11538956 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_033756250.1 → XP_033612141.1  disintegrin and metalloproteinase domain-containing protein 10

    UniProtKB/TrEMBL
    A0A091D6B9
    Conserved Domains (3) summary
    smart00050
    Location:392 → 471
    DISIN; Homologues of snake disintegrins
    cd04270
    Location:146 → 385
    ZnMc_TACE_like; Zinc-dependent metalloprotease; TACE_like subfamily. TACE, the tumor-necrosis factor-alpha converting enzyme, releases soluble TNF-alpha from transmembrane pro-TNF-alpha.
    pfam01562
    Location:2 → 82
    Pep_M12B_propep; Reprolysin family propeptide
Nucleotide Protein
Heading Accession and Version

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