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ILK integrin linked kinase [ Haliaeetus leucocephalus (bald eagle) ]

Gene ID: 104837527, updated on 3-Aug-2024

Summary

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Gene symbol
ILK
Gene description
integrin linked kinase
Gene type
protein coding
RefSeq status
MODEL
Organism
Haliaeetus leucocephalus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Accipitrimorphae; Accipitriformes; Accipitridae; Accipitrinae; Haliaeetus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
14
Annotation release Status Assembly Chr Location
100 current Haliaeetus_leucocephalus-4.0 (GCF_000737465.1) Unplaced Scaffold NW_010972972.1 (7806337..7812931)

NW_010972972.1Genomic Context describing neighboring genes Neighboring gene ADP ribosylation factor interacting protein 2 Neighboring gene translocase of inner mitochondrial membrane 10B Neighboring gene ribosomal RNA processing 8 Neighboring gene tripeptidyl peptidase 1 Neighboring gene dachsous cadherin-related 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_010972972.1 Unplaced Scaffold Reference Haliaeetus_leucocephalus-4.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell-matrix adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in substrate adhesion-dependent cell spreading IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in focal adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in stress fiber IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
integrin-linked protein kinase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Haliaeetus leucocephalus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Haliaeetus_leucocephalus-4.0

Genomic

  1. NW_010972972.1 Reference Haliaeetus_leucocephalus-4.0

    Range
    7806337..7812931
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010576723.1 → XP_010575025.1  integrin-linked protein kinase isoform X2

    See identical proteins and their annotated locations for XP_010575025.1

    Conserved Domains (4) summary
    cd14057
    Location:197 → 449
    PK_ILK; Pseudokinase domain of Integrin Linked Kinase
    sd00045
    Location:33 → 64
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:4 → 54
    Ank_4; Ankyrin repeats (many copies)
    pfam12796
    Location:38 → 124
    Ank_2; Ankyrin repeats (3 copies)

  2. XM_010576721.1 → XP_010575023.1  integrin-linked protein kinase isoform X1

    Conserved Domains (6) summary
    cd00204
    Location:90 → 202
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd14057
    Location:259 → 511
    PK_ILK; Pseudokinase domain of Integrin Linked Kinase
    pfam07714
    Location:255 → 508
    Pkinase_Tyr; Protein tyrosine kinase
    pfam12796
    Location:100 → 192
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:66 → 116
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:95 → 126
    ANK; ANK repeat [structural motif]

  3. XM_010576722.1 → XP_010575024.1  integrin-linked protein kinase isoform X2

    See identical proteins and their annotated locations for XP_010575024.1

    Conserved Domains (4) summary
    cd14057
    Location:197 → 449
    PK_ILK; Pseudokinase domain of Integrin Linked Kinase
    sd00045
    Location:33 → 64
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:4 → 54
    Ank_4; Ankyrin repeats (many copies)
    pfam12796
    Location:38 → 124
    Ank_2; Ankyrin repeats (3 copies)
Nucleotide Protein
Heading Accession and Version

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