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IRAK3 interleukin 1 receptor associated kinase 3 [ Rhinopithecus roxellana (golden snub-nosed monkey) ]

Gene ID: 104675422, updated on 12-Mar-2024

Summary

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Gene symbol
IRAK3
Gene description
interleukin 1 receptor associated kinase 3
See related
Ensembl:ENSRROG00000010966
Gene type
protein coding
RefSeq status
MODEL
Organism
Rhinopithecus roxellana
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Colobinae; Rhinopithecus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 10
Exon count:
13
Annotation release Status Assembly Chr Location
101 current ASM756505v1 (GCF_007565055.1) 10 NC_044558.1 (44580753..44640654, complement)
100 previous assembly Rrox_v1 (GCF_000769185.1) Unplaced Scaffold NW_010789605.1 (1247942..1302155, complement)

Chromosome 10 - NC_044558.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA U13 Neighboring gene DNA helicase B Neighboring gene transmembrane BAX inhibitor motif containing 4 Neighboring gene LLP homolog, long-term synaptic facilitation factor

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in interleukin-1-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of MAP kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of interleukin-12 production IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of tumor necrosis factor production IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of NF-kappaB transcription factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
interleukin-1 receptor-associated kinase 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Rhinopithecus roxellana Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM756505v1 Primary Assembly

Genomic

  1. NC_044558.1 Reference ASM756505v1 Primary Assembly

    Range
    44580753..44640654 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010379978.2 → XP_010378280.2  interleukin-1 receptor-associated kinase 3 isoform X1

    UniProtKB/TrEMBL
    A0A2K6NEL7
    Conserved Domains (2) summary
    cd08796
    Location:15 → 103
    Death_IRAK-M; Death domain of Interleukin 1 Receptor Associated Kinase-M
    cd14160
    Location:171 → 446
    PK_IRAK3; Pseudokinase domain of Interleukin-1 Receptor Associated Kinase 3

  2. XM_010379987.2 → XP_010378289.2  interleukin-1 receptor-associated kinase 3 isoform X3

    UniProtKB/TrEMBL
    A0A2K6NEL9
    Conserved Domains (2) summary
    cd14160
    Location:110 → 385
    PK_IRAK3; Pseudokinase domain of Interleukin-1 Receptor Associated Kinase 3
    cl14633
    Location:15 → 61
    DD; Death Domain Superfamily of protein-protein interaction domains

  3. XM_030938718.1 → XP_030794578.1  interleukin-1 receptor-associated kinase 3 isoform X2

    UniProtKB/TrEMBL
    A0A2K6NEL9
    Conserved Domains (1) summary
    cd14160
    Location:117 → 392
    PK_IRAK3; Pseudokinase domain of Interleukin-1 Receptor Associated Kinase 3
Nucleotide Protein
Heading Accession and Version

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