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HGF hepatocyte growth factor [ Haliaeetus albicilla (white-tailed eagle) ]

Gene ID: 104320775, updated on 3-Aug-2024

Summary

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Gene symbol
HGF
Gene description
hepatocyte growth factor
Locus tag
N329_10655
Gene type
protein coding
RefSeq status
MODEL
Organism
Haliaeetus albicilla
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Accipitrimorphae; Accipitriformes; Accipitridae; Accipitrinae; Haliaeetus
Annotation information
Annotation category: partial on reference assembly
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
18
Annotation release Status Assembly Chr Location
100 current ASM69140v1 (GCF_000691405.1) Unplaced Scaffold NW_009780715.1 (2298..54891, complement)

NW_009780715.1Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_009780715.1 Unplaced Scaffold Reference ASM69140v1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in hepatocyte growth factor receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hepatocyte growth factor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Haliaeetus albicilla Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM69140v1

Genomic

  1. NW_009780715.1 Reference ASM69140v1

    Range
    2298..54891 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009923152.1 → XP_009921454.1  hepatocyte growth factor

    UniProtKB/TrEMBL
    A0A091PJK8
    Conserved Domains (5) summary
    smart00020
    Location:554 → 778
    Tryp_SPc; Trypsin-like serine protease
    smart00130
    Location:268 → 348
    KR; Kringle domain
    cd00108
    Location:446 → 530
    KR; Kringle domain; Kringle domains are believed to play a role in binding mediators, such as peptides, other proteins, membranes, or phospholipids. They are autonomous structural domains, found in a varying number of copies, in blood clotting and ...
    cd00190
    Location:555 → 781
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    cd01099
    Location:97 → 180
    PAN_AP_HGF; Subfamily of PAN/APPLE-like domains; present in N-terminal (N) domains of plasminogen/hepatocyte growth factor proteins, and various proteins found in Bilateria, such as leech anti-platelet proteins. PAN/APPLE domains fulfill diverse biological functions ...
Nucleotide Protein
Heading Accession and Version

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