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NOS2 nitric oxide synthase 2 [ Ursus maritimus (polar bear) ]

Gene ID: 103667420, updated on 11-Mar-2024

Summary

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Gene symbol
NOS2
Gene description
nitric oxide synthase 2
See related
Ensembl:ENSUMAG00000012259
Gene type
protein coding
RefSeq status
MODEL
Organism
Ursus maritimus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
25
Annotation release Status Assembly Chr Location
101 current ASM1731132v1 (GCF_017311325.1) Unplaced Scaffold NW_024424897.1 (40585325..40617044, complement)
100 previous assembly UrsMar_1.0 (GCF_000687225.1) Unplaced Scaffold NW_007907141.1 (5574605..5604169)

NW_024424897.1Genomic Context describing neighboring genes Neighboring gene WD repeat and SOCS box containing 1 Neighboring gene uncharacterized LOC103667243 Neighboring gene kinase suppressor of ras 1 Neighboring gene galectin-9 Neighboring gene U1 small nuclear ribonucleoprotein C-like Neighboring gene LYR motif containing 9 Neighboring gene small nucleolar RNA U3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables FMN binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables NADP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calmodulin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables flavin adenine dinucleotide binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables heme binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nitric-oxide synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in nitric oxide biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
nitric oxide synthase, inducible

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Ursus maritimus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1731132v1 Primary Assembly

Genomic

  1. NW_024424897.1 Reference ASM1731132v1 Primary Assembly

    Range
    40585325..40617044 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040641031.1 → XP_040496965.1  nitric oxide synthase, inducible

    UniProtKB/TrEMBL
    A0A452UBF5, A0A8M1GPI1
    Conserved Domains (3) summary
    cd00795
    Location:55 → 467
    NOS_oxygenase_euk; Nitric oxide synthase (NOS) eukaryotic oxygenase domain. NOS produces nitric oxide (NO) by catalyzing a five-electron heme-based oxidation of a guanidine nitrogen of L-arginine to L-citrulline via two successive monooxygenation reactions producing N ...
    cl00438
    Location:551 → 627
    FMN_red; NADPH-dependent FMN reductase
    cl06868
    Location:707 → 1103
    FNR_like; Ferredoxin reductase (FNR), an FAD and NAD(P) binding protein, was intially identified as a chloroplast reductase activity, catalyzing the electron transfer from reduced iron-sulfur protein ferredoxin to NADP+ as the final step in the electron transport ...
Nucleotide Protein
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