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AGO2 argonaute RISC catalytic component 2 [ Carlito syrichta (Philippine tarsier) ]

Gene ID: 103276616, updated on 11-Mar-2024

Summary

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Gene symbol
AGO2
Gene description
argonaute RISC catalytic component 2
See related
Ensembl:ENSTSYG00000007281
Gene type
protein coding
RefSeq status
MODEL
Organism
Carlito syrichta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Tarsiiformes; Tarsiidae; Carlito
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
18
Annotation release Status Assembly Chr Location
101 current Tarsius_syrichta-2.0.1 (GCF_000164805.1) Unplaced Scaffold NW_007260371.1 (906810..965635, complement)

NW_007260371.1Genomic Context describing neighboring genes Neighboring gene up-regulated during skeletal muscle growth protein 5 pseudogene Neighboring gene uncharacterized LOC103276621

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_007260371 Unplaced Scaffold Reference Tarsius_syrichta-2.0.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables endoribonuclease activity, cleaving siRNA-paired mRNA IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulatory ncRNA-mediated gene silencing IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of RISC complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protein argonaute-2
Names
argonaute 2, RISC catalytic component

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Carlito syrichta Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Tarsius_syrichta-2.0.1 Primary Assembly

Genomic

  1. NW_007260371.1 Reference Tarsius_syrichta-2.0.1 Primary Assembly

    Range
    906810..965635 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008074024.2 → XP_008072215.1  protein argonaute-2 isoform X2

    UniProtKB/TrEMBL
    A0A1U7UPS9
    Related
    ENSTSYP00000030964.1, ENSTSYT00000033121.1
    Conserved Domains (5) summary
    PLN03202
    Location:1 → 778
    PLN03202; protein argonaute; Provisional
    cd02846
    Location:181 → 301
    PAZ_argonaute_like; PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille. ...
    cd04657
    Location:346 → 737
    Piwi_ago-like; Piwi_ago-like: PIWI domain, Argonaute-like subfamily. Argonaute is the central component of the RNA-induced silencing complex (RISC) and related complexes. The PIWI domain is the C-terminal portion of Argonaute and consists of two subdomains, one of ...
    pfam08699
    Location:131 → 180
    ArgoL1; Argonaute linker 1 domain
    pfam16486
    Location:1 → 120
    ArgoN; N-terminal domain of argonaute

  2. XM_008074025.2 → XP_008072216.1  protein argonaute-2 isoform X1

    UniProtKB/TrEMBL
    A0A1U7V1X7
    Related
    ENSTSYP00000029656.1, ENSTSYT00000033741.1
    Conserved Domains (4) summary
    cd02846
    Location:181 → 301
    PAZ_argonaute_like; PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille. ...
    cd04657
    Location:346 → 771
    Piwi_ago-like; PIWI domain, Argonaute-like subfamily. Argonaute is the central component of the RNA-induced silencing complex (RISC) and related complexes. The PIWI domain is the C-terminal portion of Argonaute and consists of two subdomains, one of which provides the ...
    pfam08699
    Location:130 → 180
    ArgoL1; Argonaute linker 1 domain
    pfam16486
    Location:46 → 120
    ArgoN; N-terminal domain of argonaute
Nucleotide Protein
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