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TLE4 TLE family member 4, transcriptional corepressor [ Carlito syrichta (Philippine tarsier) ]

Gene ID: 103259557, updated on 11-Mar-2024

Summary

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Gene symbol
TLE4
Gene description
TLE family member 4, transcriptional corepressor
See related
Ensembl:ENSTSYG00000003421
Gene type
protein coding
RefSeq status
MODEL
Organism
Carlito syrichta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Tarsiiformes; Tarsiidae; Carlito
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
19
Annotation release Status Assembly Chr Location
101 current Tarsius_syrichta-2.0.1 (GCF_000164805.1) Unplaced Scaffold NW_007246976.1 (26938..172093)

NW_007246976.1Genomic Context describing neighboring genes Neighboring gene cytochrome P450 family 7 subfamily B member 1 Neighboring gene uncharacterized LOC110595569

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_007246976 Unplaced Scaffold Reference Tarsius_syrichta-2.0.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription corepressor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of transcription regulator complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
transducin-like enhancer protein 4
Names
transducin like enhancer of split 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Carlito syrichta Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Tarsius_syrichta-2.0.1 Primary Assembly

Genomic

  1. NW_007246976.1 Reference Tarsius_syrichta-2.0.1 Primary Assembly

    Range
    26938..172093
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008057217.1 → XP_008055408.1  transducin-like enhancer protein 4 isoform X1

    UniProtKB/TrEMBL
    A0A1U7TG75
    Related
    ENSTSYP00000003132.2, ENSTSYT00000003424.2
    Conserved Domains (4) summary
    COG2319
    Location:418 → 710
    WD40; WD40 repeat [General function prediction only]
    cd00200
    Location:425 → 709
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    pfam03920
    Location:1 → 77
    TLE_N; Groucho/TLE N-terminal Q-rich domain
    sd00039
    Location:429 → 468
    7WD40; WD40 repeat [structural motif]

  2. XM_008057218.1 → XP_008055409.1  transducin-like enhancer protein 4 isoform X2

    UniProtKB/TrEMBL
    A0A1U7T5T4
    Related
    ENSTSYP00000016190.1, ENSTSYT00000031028.1
    Conserved Domains (4) summary
    COG2319
    Location:417 → 709
    WD40; WD40 repeat [General function prediction only]
    cd00200
    Location:424 → 708
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    pfam03920
    Location:1 → 76
    TLE_N; Groucho/TLE N-terminal Q-rich domain
    sd00039
    Location:428 → 467
    7WD40; WD40 repeat [structural motif]
Nucleotide Protein
Heading Accession and Version

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