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USP45 ubiquitin specific peptidase 45 [ Physeter catodon (sperm whale) ]

Gene ID: 102977963, updated on 10-Mar-2024

Summary

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Gene symbol
USP45
Gene description
ubiquitin specific peptidase 45
See related
Ensembl:ENSPCTG00005017566
Gene type
protein coding
RefSeq status
MODEL
Organism
Physeter catodon
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Physeteridae; Physeter
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 10
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2023_04 current ASM283717v5 (GCF_002837175.3) 10 NC_041223.1 (60233806..60301308)
102 previous assembly ASM283717v2 (GCF_002837175.2) 10 NC_041223.1 (60233822..60300448)

Chromosome 10 - NC_041223.1Genomic Context describing neighboring genes Neighboring gene cyclin C Neighboring gene thiosulfate sulfurtransferase like domain containing 3 Neighboring gene PNN interacting serine and arginine rich protein Neighboring gene coenzyme Q3, methyltransferase Neighboring gene failed axon connections homolog, metaxin like GST domain containing Neighboring gene 40S ribosomal protein S12-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cysteine-type deubiquitinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein deubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ubiquitin carboxyl-terminal hydrolase 45

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002837175.3-RS_2023_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM283717v5 Primary Assembly

Genomic

  1. NC_041223.1 Reference ASM283717v5 Primary Assembly

    Range
    60233806..60301308
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_007101123.3 → XP_007101185.2  ubiquitin carboxyl-terminal hydrolase 45 isoform X1

    UniProtKB/TrEMBL
    A0A2Y9EG35
    Conserved Domains (3) summary
    cd02667
    Location:589 → 812
    Peptidase_C19K; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    pfam02148
    Location:80 → 132
    zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein
    cl02553
    Location:191 → 386
    Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...

  2. XM_055087601.1 → XP_054943576.1  ubiquitin carboxyl-terminal hydrolase 45 isoform X2

    UniProtKB/TrEMBL
    A0A9W2WWG7

  3. XM_055087605.1 → XP_054943580.1  ubiquitin carboxyl-terminal hydrolase 45 isoform X7

    UniProtKB/TrEMBL
    A0A9W2WWQ7

  4. XM_055087602.1 → XP_054943577.1  ubiquitin carboxyl-terminal hydrolase 45 isoform X4

    UniProtKB/TrEMBL
    A0A9W2WWG1

  5. XM_055087604.1 → XP_054943579.1  ubiquitin carboxyl-terminal hydrolase 45 isoform X6

    UniProtKB/TrEMBL
    A0A9W2WWR2

  6. XM_055087606.1 → XP_054943581.1  ubiquitin carboxyl-terminal hydrolase 45 isoform X8

    UniProtKB/TrEMBL
    A0A9W2WWH1

  7. XM_007101122.3 → XP_007101184.2  ubiquitin carboxyl-terminal hydrolase 45 isoform X1

    UniProtKB/TrEMBL
    A0A2Y9EG35
    Related
    ENSPCTP00005024471.1, ENSPCTT00005026967.1
    Conserved Domains (3) summary
    cd02667
    Location:589 → 812
    Peptidase_C19K; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    pfam02148
    Location:80 → 132
    zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein
    cl02553
    Location:191 → 386
    Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...

  8. XM_007101124.4 → XP_007101186.2  ubiquitin carboxyl-terminal hydrolase 45 isoform X3

    UniProtKB/TrEMBL
    A0A2Y9EFF5
    Conserved Domains (3) summary
    cd02667
    Location:508 → 731
    Peptidase_C19K; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    pfam02148
    Location:11 → 51
    zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein
    cl02553
    Location:110 → 305
    Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...

  9. XM_055087603.1 → XP_054943578.1  ubiquitin carboxyl-terminal hydrolase 45 isoform X5

    UniProtKB/TrEMBL
    A0A9W2WWX0

RNA

  1. XR_008618395.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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