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SIRT1 sirtuin 1 [ Panthera tigris (tiger) ]

Gene ID: 102963908, updated on 10-Mar-2024

Summary

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Gene symbol
SIRT1
Gene description
sirtuin 1
See related
Ensembl:ENSPTIG00000015258
Gene type
protein coding
RefSeq status
MODEL
Organism
Panthera tigris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Pantherinae; Panthera
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: D2
Exon count:
11
Annotation release Status Assembly Chr Location
102 current P.tigris_Pti1_mat1.1 (GCF_018350195.1) D2 NC_056670.1 (28506024..28552466)

Chromosome D2 - NC_056670.1Genomic Context describing neighboring genes Neighboring gene DnaJ heat shock protein family (Hsp40) member C12 Neighboring gene uncharacterized LOC102964207 Neighboring gene HECT and RLD domain containing E3 ubiquitin protein ligase 4 Neighboring gene uncharacterized LOC122231845 Neighboring gene myopalladin

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_056670.1 Chromosome D2 Reference P.tigris_Pti1_mat1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables NAD+ binding IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
NAD-dependent protein deacetylase sirtuin-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Panthera tigris Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference P.tigris_Pti1_mat1.1 Primary Assembly

Genomic

  1. NC_056670.1 Reference P.tigris_Pti1_mat1.1 Primary Assembly

    Range
    28506024..28552466
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_042960114.1 → XP_042816048.1  NAD-dependent protein deacetylase sirtuin-1 isoform X1

    Conserved Domains (1) summary
    cd01408
    Location:250 → 485
    SIRT1; Eukaryotic group (class1) which includes human sirtuins SIRT1-3 and yeast Hst1-4; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation. Sir2 proteins ...

  2. XM_042960115.1 → XP_042816049.1  NAD-dependent protein deacetylase sirtuin-1 isoform X3

    UniProtKB/TrEMBL
    A0A8C9KAZ0
    Conserved Domains (1) summary
    cd01408
    Location:62 → 297
    SIRT1; Eukaryotic group (class1) which includes human sirtuins SIRT1-3 and yeast Hst1-4; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation. Sir2 proteins ...

  3. XM_015543620.2 → XP_015399106.1  NAD-dependent protein deacetylase sirtuin-1 isoform X2

    UniProtKB/TrEMBL
    A0A8C9K0Y1, A0A8C9KAZ0
    Related
    ENSPTIP00000016498.1
    Conserved Domains (1) summary
    cl00195
    Location:12 → 186
    SIR2; SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+, ...
Nucleotide Protein
Heading Accession and Version

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