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TOP2B DNA topoisomerase II beta [ Panthera tigris (tiger) ]

Gene ID: 102960613, updated on 10-Mar-2024

Summary

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Gene symbol
TOP2B
Gene description
DNA topoisomerase II beta
See related
Ensembl:ENSPTIG00000006585
Gene type
protein coding
RefSeq status
MODEL
Organism
Panthera tigris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Pantherinae; Panthera
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: C2
Exon count:
36
Annotation release Status Assembly Chr Location
102 current P.tigris_Pti1_mat1.1 (GCF_018350195.1) C2 NC_056668.1 (140830490..140894830, complement)

Chromosome C2 - NC_056668.1Genomic Context describing neighboring genes Neighboring gene retinoic acid receptor beta Neighboring gene uncharacterized LOC122230633 Neighboring gene uncharacterized LOC122230634 Neighboring gene N-glycanase 1 Neighboring gene 3-oxoacyl-ACP synthase, mitochondrial

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_056668.1 Chromosome C2 Reference P.tigris_Pti1_mat1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA topological change IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in resolution of meiotic recombination intermediates IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sister chromatid segregation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
DNA topoisomerase 2-beta
Names
topoisomerase (DNA) II beta 180kDa

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Panthera tigris Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference P.tigris_Pti1_mat1.1 Primary Assembly

Genomic

  1. NC_056668.1 Reference P.tigris_Pti1_mat1.1 Primary Assembly

    Range
    140830490..140894830 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_042956679.1 → XP_042812613.1  DNA topoisomerase 2-beta isoform X2

    UniProtKB/TrEMBL
    A0A8C9J8A9
    Conserved Domains (1) summary
    PTZ00108
    Location:39 → 1463
    PTZ00108; DNA topoisomerase 2-like protein; Provisional

  2. XM_042956678.1 → XP_042812612.1  DNA topoisomerase 2-beta isoform X1

    UniProtKB/TrEMBL
    A0A8C9J8A9
    Conserved Domains (1) summary
    PTZ00108
    Location:44 → 1468
    PTZ00108; DNA topoisomerase 2-like protein; Provisional
Nucleotide Protein
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