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SRC SRC proto-oncogene, non-receptor tyrosine kinase [ Elephantulus edwardii (Cape elephant shrew) ]

Gene ID: 102854607, updated on 10-Mar-2024

Summary

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Gene symbol
SRC
Gene description
SRC proto-oncogene, non-receptor tyrosine kinase
Gene type
protein coding
RefSeq status
MODEL
Organism
Elephantulus edwardii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Afrotheria; Macroscelidea; Macroscelididae; Elephantulus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
11
Annotation release Status Assembly Chr Location
100 current EleEdw1.0 (GCF_000299155.1) Unplaced Scaffold NW_006399765.1 (10253720..10272371)

NW_006399765.1Genomic Context describing neighboring genes Neighboring gene mannosidase beta like Neighboring gene ribosomal protein S6 pseudogene Neighboring gene uncharacterized LOC102847926 Neighboring gene BLCAP apoptosis inducing factor Neighboring gene neuronatin

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_006399765 unplaced scaffold reference EleEdw1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables growth factor receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables non-membrane spanning protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in bone resorption IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in epidermal growth factor receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in innate immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of extrinsic apoptotic signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of intrinsic apoptotic signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in osteoclast development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in progesterone receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extrinsic component of cytoplasmic side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
proto-oncogene tyrosine-protein kinase Src

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Elephantulus edwardii Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EleEdw1.0

Genomic

  1. NW_006399765.1 Reference EleEdw1.0

    Range
    10253720..10272371
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006881511.1 → XP_006881573.1  proto-oncogene tyrosine-protein kinase Src

    Conserved Domains (4) summary
    cd10365
    Location:147 → 247
    SH2_Src_Src; Src homology 2 (SH2) domain found in tyrosine kinase sarcoma (Src)
    cd12008
    Location:88 → 143
    SH3_Src; Src homology 3 domain of Src Protein Tyrosine Kinase
    cd05071
    Location:260 → 536
    PTKc_Src; Catalytic domain of the Protein Tyrosine Kinase, Src
    pfam07714
    Location:270 → 519
    Pkinase_Tyr; Protein tyrosine kinase
Nucleotide Protein
Heading Accession and Version

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