U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Smim6 small integral membrane protein 6 [ Rattus norvegicus (Norway rat) ]

Gene ID: 102552551, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
Smim6provided by RGD
Official Full Name
small integral membrane protein 6provided by RGD
Primary source
RGD:7720946
See related
EnsemblRapid:ENSRNOG00000083940 AllianceGenome:RGD:7720946
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to act upstream of or within negative regulation of ATPase-coupled calcium transmembrane transporter activity and negative regulation of calcium ion binding activity. Predicted to be located in endoplasmic reticulum membrane. Orthologous to human SMIM6 (small integral membrane protein 6). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Spleen (RPKM 21.9), Thymus (RPKM 20.9) and 9 other tissues See more
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
10q32.1
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (101643129..101652465)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (101144577..101147160)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (104461510..104470238)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene myosin XVB Neighboring gene RecQ like helicase 5 Neighboring gene small integral membrane protein 5 Neighboring gene SAP30 binding protein Neighboring gene ribosomal protein S18-like 1 Neighboring gene integrin subunit beta 4

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Widespread control of calcium signaling by a family of SERCA-inhibiting micropeptides. Anderson DM, et al. Sci Signal, 2016 Dec 6. PMID 27923914, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
acts_upstream_of_or_within negative regulation of ATPase-coupled calcium transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

Go to the top of the page Help
Preferred Names
small integral membrane protein 6

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    101643129..101652465
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063270173.1 → XP_063126243.1  small integral membrane protein 6

  2. XM_063270174.1 → XP_063126244.1  small integral membrane protein 6

    Related
    ENSRNOP00000112010.1, ENSRNOT00000149701.1

RNA

  1. XR_010055879.1 RNA Sequence

  2. XR_010055880.1 RNA Sequence

  3. XR_010055881.1 RNA Sequence

  4. XR_010055878.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.