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SQSTM1 sequestosome 1 [ Vicugna pacos (alpaca) ]

Gene ID: 102545164, updated on 10-Mar-2024

Summary

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Gene symbol
SQSTM1
Gene description
sequestosome 1
Gene type
protein coding
RefSeq status
MODEL
Organism
Vicugna pacos
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Tylopoda; Camelidae; Vicugna
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 22
Exon count:
7
Annotation release Status Assembly Chr Location
102 current VicPac3.1 (GCF_000164845.3) 22 Unlocalized Scaffold NW_021964202.1 (605890..615191, complement)
101 previous assembly Vicugna_pacos-2.0.1 (GCF_000164845.1) Unplaced Scaffold NW_005882716.1 (602391..611807, complement)

NW_021964202.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC116285034 Neighboring gene uncharacterized LOC116285035 Neighboring gene TBC1 domain family member 9B Neighboring gene MRN complex interacting protein Neighboring gene alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B Neighboring gene mastermind like transcriptional coactivator 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables K63-linked polyubiquitin modification-dependent protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase C binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in aggrephagy IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in endosome organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mitophagy IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in aggresome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in amphisome IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
sequestosome-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Vicugna pacos Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference VicPac3.1 Primary Assembly

Genomic

  1. NW_021964202.1 Reference VicPac3.1 Primary Assembly

    Range
    605890..615191 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006198917.3 → XP_006198979.1  sequestosome-1

    UniProtKB/TrEMBL
    A0A6I9HYH8
    Conserved Domains (3) summary
    cd02340
    Location:64 → 106
    ZZ_NBR1_like; Zinc finger, ZZ type. Zinc finger present in Drosophila ref(2)P, NBR1, Human sequestosome 1 and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Drosophila ref(2)P appears ...
    pfam16577
    Location:317 → 378
    UBA_5; UBA domain
    cl02720
    Location:2 → 40
    PB1; The PB1 domain is a modular domain mediating specific protein-protein interactions which play a role in many critical cell processes, such as osteoclastogenesis, angiogenesis, early cardiovascular development, and cell polarity. A canonical PB1-PB1 ...
Nucleotide Protein
Heading Accession and Version

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