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TTK TTK protein kinase [ Bos mutus (wild yak) ]

Gene ID: 102284230, updated on 10-Mar-2024

Summary

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Gene symbol
TTK
Gene description
TTK protein kinase
Locus tag
M91_12728
See related
Ensembl:ENSBMUG00000006351
Gene type
protein coding
RefSeq status
MODEL
Organism
Bos mutus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
21
Annotation release Status Assembly Chr Location
101 current BosGru_v2.0 (GCF_000298355.1) Unplaced Scaffold NW_005393642.1 (101492..143095, complement)

NW_005393642.1Genomic Context describing neighboring genes Neighboring gene 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial Neighboring gene uncharacterized LOC106700814 Neighboring gene ELOVL fatty acid elongase 4

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_005393642.1 Unplaced Scaffold Reference BosGru_v2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The yak genome and adaptation to life at high altitude. Qiu Q, et al. Nat Genet, 2012 Jul 1. PMID 22751099

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine/tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in chromosome segregation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in meiotic spindle assembly checkpoint signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mitotic spindle assembly checkpoint signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptidyl-serine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein localization to kinetochore IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in kinetochore IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in spindle IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
dual specificity protein kinase TTK
Names
Dual specificity protein kinase TTK

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Bos mutus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference BosGru_v2.0 Primary Assembly

Genomic

  1. NW_005393642.1 Reference BosGru_v2.0 Primary Assembly

    Range
    101492..143095 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_014478049.1 → XP_014333535.1  dual specificity protein kinase TTK isoform X2

    UniProtKB/TrEMBL
    A0A6B0QRY4
    Conserved Domains (3) summary
    cd14131
    Location:521 → 788
    PKc_Mps1; Catalytic domain of the Dual-specificity Mitotic checkpoint protein kinase, Monopolar spindle 1 (also called TTK)
    sd00006
    Location:79 → 104
    TPR; TPR repeat [structural motif]
    pfam00069
    Location:523 → 788
    Pkinase; Protein kinase domain

  2. XM_005895139.1 → XP_005895201.1  dual specificity protein kinase TTK isoform X1

    See identical proteins and their annotated locations for XP_005895201.1

    UniProtKB/TrEMBL
    A0A6B0QRY4, L8IL40
    Related
    ENSBMUP00000008097.1, ENSBMUT00000009461.1
    Conserved Domains (3) summary
    cd14131
    Location:522 → 789
    PKc_Mps1; Catalytic domain of the Dual-specificity Mitotic checkpoint protein kinase, Monopolar spindle 1 (also called TTK)
    sd00006
    Location:79 → 104
    TPR; TPR repeat [structural motif]
    pfam00069
    Location:524 → 789
    Pkinase; Protein kinase domain
Nucleotide Protein
Heading Accession and Version

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