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PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta [ Geospiza fortis (medium ground-finch) ]

Gene ID: 102040853, updated on 3-Aug-2024

Summary

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Gene symbol
PIK3CD
Gene description
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
See related
Ensembl:ENSGFOG00000011223
Gene type
protein coding
RefSeq status
MODEL
Organism
Geospiza fortis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves; Passeriformes; Thraupidae; Geospiza
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
23
Annotation release Status Assembly Chr Location
102 current GeoFor_1.0 (GCF_000277835.1) Unplaced Scaffold NW_005054450.1 (1033787..1051039)

NW_005054450.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 25 member 33 Neighboring gene transmembrane protein 201 Neighboring gene calsyntenin 1 Neighboring gene catenin beta interacting protein 1 Neighboring gene leucine zipper and CTNNBIP1 domain containing Neighboring gene nicotinamide nucleotide adenylyltransferase 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_005054450 Unplaced Scaffold Reference GeoFor_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables 1-phosphatidylinositol-4-phosphate 3-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-3-phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of phosphatidylinositol 3-kinase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Geospiza fortis Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GeoFor_1.0

Genomic

  1. NW_005054450.1 Reference GeoFor_1.0

    Range
    1033787..1051039
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005427686.2 → XP_005427743.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1

    UniProtKB/TrEMBL
    A0A6I9HPR3
    Related
    ENSGFOP00000016729.1, ENSGFOT00000017278.1
    Conserved Domains (5) summary
    cd08693
    Location:313 → 479
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    cd05174
    Location:677 → 1042
    PI3Kc_IA_delta; Catalytic domain of Class IA Phosphoinositide 3-kinase delta
    cl00271
    Location:507 → 676
    PI3Ka; Phosphoinositide 3-kinase family, accessory domain (PIK domain); PIK domain is conserved in PI3 and PI4-kinases. Its role is unclear, but it has been suggested to be involved in substrate presentation. Phosphoinositide 3-kinases play an important role in ...
    pfam02192
    Location:32 → 107
    PI3K_p85B; PI3-kinase family, p85-binding domain
    cl02484
    Location:183 → 279
    PI3K_rbd; PI3-kinase family, ras-binding domain

  2. XM_031062554.1 → XP_030918414.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X2

    UniProtKB/TrEMBL
    A0A8N5I2Q0
    Conserved Domains (5) summary
    cd08693
    Location:295 → 461
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    cd05174
    Location:659 → 1024
    PI3Kc_IA_delta; Catalytic domain of Class IA Phosphoinositide 3-kinase delta
    cl00271
    Location:489 → 658
    PI3Ka; Phosphoinositide 3-kinase family, accessory domain (PIK domain); PIK domain is conserved in PI3 and PI4-kinases. Its role is unclear, but it has been suggested to be involved in substrate presentation. Phosphoinositide 3-kinases play an important role in ...
    pfam02192
    Location:32 → 107
    PI3K_p85B; PI3-kinase family, p85-binding domain
    cl02484
    Location:183 → 261
    PI3K_rbd; PI3-kinase family, ras-binding domain
Nucleotide Protein
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