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Sesn2 sestrin 2 [ Ictidomys tridecemlineatus (thirteen-lined ground squirrel) ]

Gene ID: 101967136, updated on 11-Apr-2024

Summary

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Gene symbol
Sesn2
Gene description
sestrin 2
Locus tag
H1C71_033141
See related
EnsemblRapid:ENSSTOG00015013085
Gene type
protein coding
RefSeq status
MODEL
Organism
Ictidomys tridecemlineatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae; Xerinae; Marmotini; Ictidomys
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
10
Annotation release Status Assembly Chr Location
103 current HiC_Itri_2 (GCF_016881025.1) Unplaced Scaffold NW_024405058.1 (46591898..46611063)
102 previous assembly SpeTri2.0 (GCF_000236235.1) Unplaced Scaffold NW_004936474.1 (12416652..12436799)

NW_024405058.1Genomic Context describing neighboring genes Neighboring gene DnaJ heat shock protein family (Hsp40) member C8 Neighboring gene ATP synthase inhibitory factor subunit 1 Neighboring gene ribosomal biogenesis factor-like Neighboring gene mediator complex subunit 18

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables L-leucine binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables oxidoreductase activity, acting on peroxide as acceptor IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to L-leucine IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to leucine starvation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of TORC1 signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of macroautophagy IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of response to reactive oxygen species IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
sestrin-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Ictidomys tridecemlineatus Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HiC_Itri_2 Primary Assembly

Genomic

  1. NW_024405058.1 Reference HiC_Itri_2 Primary Assembly

    Range
    46591898..46611063
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021734701.2 → XP_021590376.1  sestrin-2 isoform X1

    Conserved Domains (1) summary
    pfam04636
    Location:42 → 532
    PA26; PA26 p53-induced protein (sestrin)

  2. XM_005317684.4 → XP_005317741.1  sestrin-2 isoform X2

    UniProtKB/TrEMBL
    I3MDA5
    Related
    ENSSTOP00015015971.1, ENSSTOT00015017547.1
    Conserved Domains (1) summary
    pfam04636
    Location:42 → 478
    PA26; PA26 p53-induced protein (sestrin)
Nucleotide Protein
Heading Accession and Version

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