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MARCHF8 membrane associated ring-CH-type finger 8 [ Anas platyrhynchos (mallard) ]

Gene ID: 101798693, updated on 8-Mar-2024

Summary

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Gene symbol
MARCHF8
Gene description
membrane associated ring-CH-type finger 8
Locus tag
Anapl_06397
See related
EnsemblRapid:ENSAPLG00030001348
Gene type
protein coding
RefSeq status
MODEL
Organism
Anas platyrhynchos
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae; Anatinae; Anas
Also known as
MARCH8
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 6
Exon count:
12
Annotation release Status Assembly Chr Location
104 current ZJU1.0 (GCF_015476345.1) 6 NC_051777.1 (17836103..17927344, complement)
103 previous assembly IASCAAS_PekingDuck_PBH1.5 (GCF_003850225.1) 6 NC_040051.1 (19920788..20015976)

Chromosome 6 - NC_051777.1Genomic Context describing neighboring genes Neighboring gene cytochrome P450 2H1 Neighboring gene arachidonate 5-lipoxygenase Neighboring gene zinc finger AN1-type containing 4 Neighboring gene WASH complex subunit 2C

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables MHC protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in antigen processing and presentation of peptide antigen via MHC class II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein polyubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in early endosome membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in late endosome membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in lysosome IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
E3 ubiquitin-protein ligase MARCHF8
Names
E3 ubiquitin-protein ligase MARCH8

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Anas platyrhynchos Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ZJU1.0 Primary Assembly

Genomic

  1. NC_051777.1 Reference ZJU1.0 Primary Assembly

    Range
    17836103..17927344 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027460086.2 → XP_027315887.1  E3 ubiquitin-protein ligase MARCHF8 isoform X1

    UniProtKB/TrEMBL
    A0A493T2L3

  2. XM_027460087.2 → XP_027315888.1  E3 ubiquitin-protein ligase MARCHF8 isoform X4

    UniProtKB/TrEMBL
    A0A493TT02, A0A493TTX3, A0A8B9ZHK4
    Related
    ENSAPLP00030003053.1, ENSAPLT00030003741.1

  3. XM_013104765.4 → XP_012960219.1  E3 ubiquitin-protein ligase MARCHF8 isoform X1

    See identical proteins and their annotated locations for XP_012960219.1

    UniProtKB/TrEMBL
    A0A493T2L3
    Conserved Domains (1) summary
    cd16698
    Location:357 → 407
    RING_CH-C4HC3_MARCH1_like; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING finger protein MARCH1, MARCH8, and similar proteins

  4. XM_021276127.3 → XP_021131802.1  E3 ubiquitin-protein ligase MARCHF8 isoform X1

    UniProtKB/TrEMBL
    A0A493T2L3
    Related
    ENSAPLP00030003067.1, ENSAPLT00030003757.1
    Conserved Domains (1) summary
    cd16698
    Location:357 → 407
    RING_CH-C4HC3_MARCH1_like; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING finger protein MARCH1, MARCH8, and similar proteins

  5. XM_013104768.4 → XP_012960222.1  E3 ubiquitin-protein ligase MARCHF8 isoform X3

    UniProtKB/TrEMBL
    A0A493T2L3
    Related
    ENSAPLP00030003030.1, ENSAPLT00030003713.1
    Conserved Domains (1) summary
    smart00744
    Location:328 → 375
    RINGv; The RING-variant domain is a C4HC3 zinc-finger like motif found in a number of cellular and viral proteins

  6. XM_038181111.1 → XP_038037039.1  E3 ubiquitin-protein ligase MARCHF8 isoform X2

    UniProtKB/TrEMBL
    A0A493T2L3
    Conserved Domains (1) summary
    cd16698
    Location:339 → 389
    RING_CH-C4HC3_MARCH1_like; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING finger protein MARCH1, MARCH8, and similar proteins
Nucleotide Protein
Heading Accession and Version

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