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Man2a2 mannosidase alpha class 2A member 2 [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101717094, updated on 8-Mar-2024

Summary

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Gene symbol
Man2a2
Gene description
mannosidase alpha class 2A member 2
See related
Ensembl:ENSHGLG00000012371
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
25
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624768.1 (17323068..17345462, complement)

NW_004624768.1Genomic Context describing neighboring genes Neighboring gene protein regulator of cytokinesis 1 Neighboring gene RCC1 domain containing 1 Neighboring gene unc-45 myosin chaperone A Neighboring gene HD domain containing 3 Neighboring gene SH2B adapter protein 1 pseudogene Neighboring gene FES proto-oncogene, tyrosine kinase

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004624768 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables alpha-mannosidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in N-glycan processing IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mannose metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein deglycosylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
alpha-mannosidase 2x

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624768.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    17323068..17345462 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021264833.1 → XP_021120492.1  alpha-mannosidase 2x isoform X1

    UniProtKB/TrEMBL
    G5CAB5
    Conserved Domains (1) summary
    PLN02701
    Location:136 → 1188
    PLN02701; alpha-mannosidase

  2. XM_004852807.3 → XP_004852864.1  alpha-mannosidase 2x isoform X4

    UniProtKB/TrEMBL
    G5CAB5
    Related
    ENSHGLP00000017282.1, ENSHGLT00000017455.1
    Conserved Domains (4) summary
    PLN02701
    Location:136 → 1149
    PLN02701; alpha-mannosidase
    smart00872
    Location:503 → 588
    Alpha-mann_mid; Alpha mannosidase, middle domain
    pfam07748
    Location:761 → 1145
    Glyco_hydro_38C; Glycosyl hydrolases family 38 C-terminal domain
    cl15692
    Location:165 → 508
    CE4_SF; Catalytic NodB homology domain of the carbohydrate esterase 4 superfamily

  3. XM_021264834.1 → XP_021120493.1  alpha-mannosidase 2x isoform X2

    UniProtKB/TrEMBL
    G5CAB5
    Conserved Domains (1) summary
    PLN02701
    Location:136 → 1174
    PLN02701; alpha-mannosidase

  4. XM_021264835.1 → XP_021120494.1  alpha-mannosidase 2x isoform X3

    UniProtKB/TrEMBL
    G5CAB5
    Conserved Domains (1) summary
    PLN02701
    Location:136 → 1163
    PLN02701; alpha-mannosidase

  5. XM_021264836.1 → XP_021120495.1  alpha-mannosidase 2x isoform X5

    UniProtKB/TrEMBL
    G5CAB5
    Conserved Domains (1) summary
    PLN02701
    Location:1 → 990
    PLN02701; alpha-mannosidase
Nucleotide Protein
Heading Accession and Version

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