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Mki67 marker of proliferation Ki-67 [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101715751, updated on 8-Mar-2024

Summary

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Gene symbol
Mki67
Gene description
marker of proliferation Ki-67
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
16
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624737.1 (18935686..18963907)

NW_004624737.1Genomic Context describing neighboring genes Neighboring gene condensin complex subunit 3-like Neighboring gene 60S ribosomal protein L9 pseudogene Neighboring gene protein tyrosine phosphatase receptor type E Neighboring gene clarin 3

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004624737 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of chromosome segregation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of mitotic nuclear division IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
proliferation marker protein Ki-67
Names
antigen identified by monoclonal antibody Ki-67

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624737.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    18935686..18963907
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021253269.1 → XP_021108928.1  proliferation marker protein Ki-67 isoform X2

    UniProtKB/TrEMBL
    G5BTI0
    Conserved Domains (3) summary
    cd00060
    Location:8 → 98
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    pfam08065
    Location:1464 → 1575
    K167R; K167R (NUC007) repeat
    pfam15276
    Location:386 → 432
    PP1_bind; Protein phosphatase 1 binding

  2. XM_004838729.3 → XP_004838786.1  proliferation marker protein Ki-67 isoform X1

    UniProtKB/TrEMBL
    G5BTI0
    Conserved Domains (4) summary
    COG1716
    Location:5 → 92
    FHA; Forkhead associated (FHA) domain, binds pSer, pThr, pTyr [Signal transduction mechanisms]
    cd00060
    Location:8 → 98
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    pfam08065
    Location:1466 → 1575
    K167R; K167R (NUC007) repeat
    pfam15276
    Location:386 → 440
    PP1_bind; Protein phosphatase 1 binding

  3. XM_021253270.1 → XP_021108929.1  proliferation marker protein Ki-67 isoform X3

    UniProtKB/TrEMBL
    G5BTI0
    Conserved Domains (3) summary
    cd00060
    Location:8 → 98
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    pfam08065
    Location:1221 → 1332
    K167R; K167R (NUC007) repeat
    pfam15276
    Location:143 → 189
    PP1_bind; Protein phosphatase 1 binding
Nucleotide Protein
Heading Accession and Version

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