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KMT2C lysine methyltransferase 2C [ Odobenus rosmarus divergens (Pacific walrus) ]

Gene ID: 101365628, updated on 8-Mar-2024

Summary

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Gene symbol
KMT2C
Gene description
lysine methyltransferase 2C
Gene type
protein coding
RefSeq status
MODEL
Organism
Odobenus rosmarus divergens (sub-species: divergens)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Odobenidae; Odobenus
Also known as
MLL3
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
59
Annotation release Status Assembly Chr Location
101 current Oros_1.0 (GCF_000321225.1) Unplaced Scaffold NW_004450664.1 (1056607..1326580, complement)

NW_004450664.1Genomic Context describing neighboring genes Neighboring gene polypeptide N-acetylgalactosaminyltransferase like 5 Neighboring gene polypeptide N-acetylgalactosaminyltransferase 11 Neighboring gene dynein light chain 1, cytoplasmic-like Neighboring gene chaperonin containing TCP1 subunit 8 like 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004450664.1 Unplaced Scaffold Reference Oros_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables histone H3K4 methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables histone binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription coactivator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of MLL3/4 complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
histone-lysine N-methyltransferase 2C
Names
myeloid/lymphoid or mixed-lineage leukemia 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Odobenus rosmarus divergens Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Oros_1.0 Primary Assembly

Genomic

  1. NW_004450664.1 Reference Oros_1.0 Primary Assembly

    Range
    1056607..1326580 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004408838.1 → XP_004408895.1  histone-lysine N-methyltransferase 2C

    UniProtKB/TrEMBL
    A0A2U3WJ91
    Conserved Domains (17) summary
    PHA03195
    Location:1865 → 2137
    PHA03195; tegument protein VP11/12; Provisional
    smart00317
    Location:4762 → 4883
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
    smart00508
    Location:4885 → 4901
    PostSET; Cysteine-rich motif following a subset of SET domains
    COG2940
    Location:4715 → 4901
    SET; SET domain-containing protein (function unknown) [General function prediction only]
    sd00025
    Location:1081 → 1103
    zf-RanBP2; RanBP2-type Zn finger [structural motif]
    cd15509
    Location:343 → 388
    PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
    cd15511
    Location:466 → 517
    PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
    cd15513
    Location:1006 → 1052
    PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
    cd15594
    Location:390 → 435
    PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
    cd15596
    Location:949 → 1005
    PHD4_KMT2C; PHD finger 4 found in Histone-lysine N-methyltransferase 2C (KMT2C)
    cd15600
    Location:1083 → 1133
    PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
    cd15696
    Location:247 → 330
    ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
    cd15697
    Location:4392 → 4496
    ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
    pfam05964
    Location:4542 → 4592
    FYRN; F/Y-rich N-terminus
    pfam05965
    Location:4598 → 4679
    FYRC; F/Y rich C-terminus
    pfam15233
    Location:3181 → 3274
    SYCE1; Synaptonemal complex central element protein 1
    cl00082
    Location:1654 → 1705
    HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
Nucleotide Protein
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