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MECOM MDS1 and EVI1 complex locus [ Tursiops truncatus (common bottlenose dolphin) ]

Gene ID: 101330677, updated on 8-Mar-2024

Summary

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Gene symbol
MECOM
Gene description
MDS1 and EVI1 complex locus
See related
EnsemblRapid:ENSTTRG00000002158
Gene type
protein coding
RefSeq status
MODEL
Organism
Tursiops truncatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Delphinidae; Tursiops
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 4
Exon count:
19
Annotation release Status Assembly Chr Location
102 current mTurTru1.mat.Y (GCF_011762595.1) 4 NC_047037.1 (46888832..47457919, complement)
101 previous assembly NIST Tur_tru v1 (GCF_001922835.1) Unplaced Scaffold NW_017843983.1 (18929521..18989970)

Chromosome 4 - NC_047037.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC109551924 Neighboring gene uncharacterized LOC117312134 Neighboring gene transfer RNA valine (anticodon AAC) Neighboring gene actin related protein T3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription activator activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables histone H3K9 methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
histone-lysine N-methyltransferase MECOM

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Tursiops truncatus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mTurTru1.mat.Y Primary Assembly

Genomic

  1. NC_047037.1 Reference mTurTru1.mat.Y Primary Assembly

    Range
    46888832..47457919 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_033855454.1 → XP_033711345.1  histone-lysine N-methyltransferase MECOM isoform X10

    UniProtKB/TrEMBL
    A0A6J3R915
    Conserved Domains (3) summary
    COG5048
    Location:289 → 729
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:590 → 610
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd19214
    Location:47 → 204
    PR-SET_PRDM3; PR-SET domain found in MDS1 and EVI1 complex locus protein and similar proteins

  2. XM_033855447.1 → XP_033711338.1  histone-lysine N-methyltransferase MECOM isoform X4

    UniProtKB/TrEMBL
    A0A6J3RBW0
    Conserved Domains (6) summary
    PHA00733
    Location:845 → 964
    PHA00733; hypothetical protein
    COG5189
    Location:302 → 395
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:914 → 934
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd19214
    Location:47 → 204
    PR-SET_PRDM3; PR-SET domain found in MDS1 and EVI1 complex locus protein and similar proteins
    pfam00096
    Location:912 → 934
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:926 → 950
    zf-H2C2_2; Zinc-finger double domain

  3. XM_033855446.1 → XP_033711337.1  histone-lysine N-methyltransferase MECOM isoform X3

    UniProtKB/TrEMBL
    A0A6J3R9R2
    Conserved Domains (6) summary
    PHA00733
    Location:846 → 965
    PHA00733; hypothetical protein
    COG5189
    Location:344 → 396
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:915 → 935
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd19214
    Location:47 → 204
    PR-SET_PRDM3; PR-SET domain found in MDS1 and EVI1 complex locus protein and similar proteins
    pfam00096
    Location:913 → 935
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:927 → 951
    zf-H2C2_2; Zinc-finger double domain

  4. XM_033855453.1 → XP_033711344.1  histone-lysine N-methyltransferase MECOM isoform X9

    UniProtKB/TrEMBL
    A0A6J3RA58
    Related
    ENSTTRP00000023226.1, ENSTTRT00000027847.1
    Conserved Domains (6) summary
    PHA00733
    Location:657 → 776
    PHA00733; hypothetical protein
    sd00017
    Location:726 → 746
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl40432
    Location:1 → 16
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain superfamily
    pfam00096
    Location:724 → 746
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:738 → 762
    zf-H2C2_2; Zinc-finger double domain
    cd20908
    Location:136 → 178
    SUF4-like; N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins

  5. XM_033855455.1 → XP_033711346.1  histone-lysine N-methyltransferase MECOM isoform X11

    UniProtKB/TrEMBL
    A0A6J3R977
    Conserved Domains (4) summary
    COG5048
    Location:101 → 541
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:402 → 422
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl40432
    Location:1 → 16
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain superfamily
    pfam13465
    Location:414 → 438
    zf-H2C2_2; Zinc-finger double domain

  6. XM_033855452.1 → XP_033711343.1  histone-lysine N-methyltransferase MECOM isoform X8

    UniProtKB/TrEMBL
    A0A6J3RBW1

  7. XM_033855445.1 → XP_033711336.1  histone-lysine N-methyltransferase MECOM isoform X2

    UniProtKB/TrEMBL
    A0A6J3R966
    Related
    ENSTTRP00000002022.2, ENSTTRT00000002155.2
    Conserved Domains (6) summary
    PHA00733
    Location:877 → 973
    PHA00733; hypothetical protein
    COG5189
    Location:302 → 395
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:923 → 943
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd19214
    Location:47 → 204
    PR-SET_PRDM3; PR-SET domain found in MDS1 and EVI1 complex locus protein and similar proteins
    pfam00096
    Location:921 → 943
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:935 → 959
    zf-H2C2_2; Zinc-finger double domain

  8. XM_033855444.1 → XP_033711335.1  histone-lysine N-methyltransferase MECOM isoform X1

    UniProtKB/TrEMBL
    A0A6J3R906
    Conserved Domains (6) summary
    PHA00733
    Location:878 → 974
    PHA00733; hypothetical protein
    COG5189
    Location:344 → 396
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:924 → 944
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd19214
    Location:47 → 204
    PR-SET_PRDM3; PR-SET domain found in MDS1 and EVI1 complex locus protein and similar proteins
    pfam00096
    Location:922 → 944
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:936 → 960
    zf-H2C2_2; Zinc-finger double domain

  9. XM_033855449.1 → XP_033711340.1  histone-lysine N-methyltransferase MECOM isoform X6

    UniProtKB/TrEMBL
    A0A6J3R972
    Related
    ENSTTRP00000030637.1, ENSTTRT00000032867.1

  10. XM_033855451.1 → XP_033711342.1  histone-lysine N-methyltransferase MECOM isoform X7

    UniProtKB/TrEMBL
    A0A6J3R9R7
    Related
    ENSTTRP00000031019.1, ENSTTRT00000044051.1

  11. XM_033855450.1 → XP_033711341.1  histone-lysine N-methyltransferase MECOM isoform X6

    UniProtKB/TrEMBL
    A0A6J3R972

  12. XM_033855448.1 → XP_033711339.1  histone-lysine N-methyltransferase MECOM isoform X5

    UniProtKB/TrEMBL
    A0A6J3RA53
    Conserved Domains (6) summary
    PHA00733
    Location:878 → 974
    PHA00733; hypothetical protein
    COG5189
    Location:344 → 396
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:924 → 944
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd19214
    Location:47 → 204
    PR-SET_PRDM3; PR-SET domain found in MDS1 and EVI1 complex locus protein and similar proteins
    pfam00096
    Location:922 → 944
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:936 → 960
    zf-H2C2_2; Zinc-finger double domain
Nucleotide Protein
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