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AXL AXL receptor tyrosine kinase [ Tursiops truncatus (common bottlenose dolphin) ]

Gene ID: 101326993, updated on 11-Apr-2024

Summary

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Gene symbol
AXL
Gene description
AXL receptor tyrosine kinase
See related
EnsemblRapid:ENSTTRG00000007032
Gene type
protein coding
RefSeq status
MODEL
Organism
Tursiops truncatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Delphinidae; Tursiops
Orthologs
human mouse all
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Genomic context

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See AXL in Genome Data Viewer
Location:
chromosome: 19
Exon count:
20
Annotation release Status Assembly Chr Location
102 current mTurTru1.mat.Y (GCF_011762595.1) 19 NC_047052.1 (46704664..46735877)
101 previous assembly NIST Tur_tru v1 (GCF_001922835.1) Unplaced Scaffold NW_017843033.1 (214857..219592)

Chromosome 19 - NC_047052.1Genomic Context describing neighboring genes Neighboring gene cytochrome P450 2F5-like Neighboring gene cytochrome P450 2S1-like Neighboring gene transfer RNA aspartic acid (anticodon AUC) Neighboring gene heterogeneous nuclear ribonucleoprotein U like 1 Neighboring gene coiled-coil domain containing 97

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane receptor protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in natural killer cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nervous system development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phagocytosis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in platelet activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tyrosine-protein kinase receptor UFO

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Tursiops truncatus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mTurTru1.mat.Y Primary Assembly

Genomic

  1. NC_047052.1 Reference mTurTru1.mat.Y Primary Assembly

    Range
    46704664..46735877
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_033845397.1 → XP_033701288.1  tyrosine-protein kinase receptor UFO isoform X1

    UniProtKB/TrEMBL
    A0A6J3QGX7
    Related
    ENSTTRP00000006689.2, ENSTTRT00000007071.2
    Conserved Domains (6) summary
    cd00063
    Location:218 → 321
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05075
    Location:528 → 804
    PTKc_Axl; Catalytic domain of the Protein Tyrosine Kinase, Axl
    pfam00041
    Location:328 → 411
    fn3; Fibronectin type III domain
    cd00096
    Location:133 → 136
    Ig; Ig strand A [structural motif]
    cd20966
    Location:29 → 128
    IgI_1_Axl_like; First immunoglobulin (Ig)-like domain of Axl receptor tyrosine kinase (RTK), and similar domains; member of the I-set Ig domains
    cl11960
    Location:133 → 215
    Ig; Immunoglobulin domain

  2. XM_033845398.1 → XP_033701289.1  tyrosine-protein kinase receptor UFO isoform X2

    UniProtKB/TrEMBL
    A0A6J3QGG9
    Conserved Domains (5) summary
    cd00063
    Location:218 → 321
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05075
    Location:431 → 707
    PTKc_Axl; Catalytic domain of the Protein Tyrosine Kinase, Axl
    cd00096
    Location:133 → 136
    Ig; Ig strand A [structural motif]
    cd20966
    Location:29 → 128
    IgI_1_Axl_like; First immunoglobulin (Ig)-like domain of Axl receptor tyrosine kinase (RTK), and similar domains; member of the I-set Ig domains
    cl11960
    Location:133 → 215
    Ig; Immunoglobulin domain

  3. XM_033845399.1 → XP_033701290.1  tyrosine-protein kinase receptor UFO isoform X3

    UniProtKB/TrEMBL
    A0A6J3QFT6
    Conserved Domains (5) summary
    cd00063
    Location:110 → 213
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05075
    Location:420 → 696
    PTKc_Axl; Catalytic domain of the Protein Tyrosine Kinase, Axl
    pfam00041
    Location:220 → 303
    fn3; Fibronectin type III domain
    cd00096
    Location:25 → 28
    Ig; Ig strand A [structural motif]
    cl11960
    Location:25 → 107
    Ig; Immunoglobulin domain
Nucleotide Protein
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