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ITGB2 integrin subunit beta 2 [ Orcinus orca (killer whale) ]

Gene ID: 101285903, updated on 8-Mar-2024

Summary

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Gene symbol
ITGB2
Gene description
integrin subunit beta 2
See related
EnsemblRapid:ENSOORG00010007480
Gene type
protein coding
RefSeq status
MODEL
Organism
Orcinus orca
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Delphinidae; Orcinus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 5
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2023_02 current mOrcOrc1.1 (GCF_937001465.1) 5 NC_064563.1 (147746219..147772652, complement)

Chromosome 5 - NC_064563.1Genomic Context describing neighboring genes Neighboring gene ubiquitin conjugating enzyme E2 G2 Neighboring gene small ubiquitin like modifier 3 Neighboring gene PTTG1 interacting protein Neighboring gene SLX9 ribosome biogenesis factor Neighboring gene putative olfactory receptor 7A2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_064563.1 Chromosome 5 Reference mOrcOrc1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables amyloid-beta binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables integrin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell adhesion mediated by integrin IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-matrix adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell surface IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in focal adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of integrin complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
integrin beta-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_937001465.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOrcOrc1.1 Primary Assembly

Genomic

  1. NC_064563.1 Reference mOrcOrc1.1 Primary Assembly

    Range
    147746219..147772652 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004264616.3 → XP_004264664.1  integrin beta-2 isoform X3

    See identical proteins and their annotated locations for XP_004264664.1

    Related
    ENSOORP00010009170.1, ENSOORT00010010937.1
    Conserved Domains (3) summary
    smart00187
    Location:32 → 447
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    pfam07965
    Location:622 → 699
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:726 → 766
    Integrin_b_cyt; Integrin beta cytoplasmic domain

  2. XM_033418463.1 → XP_033274354.1  integrin beta-2 isoform X2

    Conserved Domains (3) summary
    smart00187
    Location:92 → 507
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    pfam07965
    Location:682 → 759
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:784 → 826
    Integrin_b_cyt; Integrin beta cytoplasmic domain

  3. XM_049710371.1 → XP_049566328.1  integrin beta-2 isoform X1

Nucleotide Protein
Heading Accession and Version

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