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GHR growth hormone receptor [ Orcinus orca (killer whale) ]

Gene ID: 101284890, updated on 8-Mar-2024

Summary

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Gene symbol
GHR
Gene description
growth hormone receptor
See related
EnsemblRapid:ENSOORG00010016029
Gene type
protein coding
RefSeq status
MODEL
Organism
Orcinus orca
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Delphinidae; Orcinus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 3
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2023_02 current mOrcOrc1.1 (GCF_937001465.1) 3 NC_064561.1 (149838656..150121741, complement)

Chromosome 3 - NC_064561.1Genomic Context describing neighboring genes Neighboring gene CCAAT/enhancer-binding protein gamma-like Neighboring gene uncharacterized LOC117199971 Neighboring gene uncharacterized LOC117199973 Neighboring gene tigger transposable element-derived protein 1-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_064561.1 Chromosome 3 Reference mOrcOrc1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cytokine binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables growth factor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables growth hormone receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables peptide hormone binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cytokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in growth hormone receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of peptidyl-tyrosine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of growth hormone receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
growth hormone receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_937001465.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOrcOrc1.1 Primary Assembly

Genomic

  1. NC_064561.1 Reference mOrcOrc1.1 Primary Assembly

    Range
    149838656..150121741 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_049708184.1 → XP_049564141.1  growth hormone receptor isoform X2

  2. XM_049708182.1 → XP_049564139.1  growth hormone receptor isoform X2

  3. XM_049708185.1 → XP_049564142.1  growth hormone receptor isoform X2

  4. XM_049708183.1 → XP_049564140.1  growth hormone receptor isoform X2

  5. XM_033421190.2 → XP_033277081.1  growth hormone receptor isoform X2

    Related
    ENSOORP00010020873.1, ENSOORT00010023850.1
    Conserved Domains (3) summary
    cd00063
    Location:149 → 250
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam12772
    Location:316 → 619
    GHBP; Growth hormone receptor binding
    cl21522
    Location:49 → 127
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

  6. XM_033421189.2 → XP_033277080.2  growth hormone receptor isoform X1

Nucleotide Protein
Heading Accession and Version

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