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MYB MYB proto-oncogene, transcription factor [ Orcinus orca (killer whale) ]

Gene ID: 101278769, updated on 8-Mar-2024

Summary

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Gene symbol
MYB
Gene description
MYB proto-oncogene, transcription factor
See related
EnsemblRapid:ENSOORG00010002987
Gene type
protein coding
RefSeq status
MODEL
Organism
Orcinus orca
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Delphinidae; Orcinus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 12
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2023_02 current mOrcOrc1.1 (GCF_937001465.1) 12 NC_064570.1 (27786389..27821432, complement)

Chromosome 12 - NC_064570.1Genomic Context describing neighboring genes Neighboring gene phosphodiesterase 7B Neighboring gene Abelson helper integration site 1 Neighboring gene uncharacterized LOC125960617 Neighboring gene U6 spliceosomal RNA Neighboring gene HBS1 like translational GTPase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_064570.1 Chromosome 12 Reference mOrcOrc1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
transcriptional activator Myb
Names
v-myb myeloblastosis viral oncogene homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_937001465.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOrcOrc1.1 Primary Assembly

Genomic

  1. NC_064570.1 Reference mOrcOrc1.1 Primary Assembly

    Range
    27786389..27821432 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004263790.3 → XP_004263838.1  transcriptional activator Myb isoform X4

    Related
    ENSOORP00010003187.1, ENSOORT00010004166.1
    Conserved Domains (4) summary
    smart00717
    Location:92 → 140
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    pfam00249
    Location:92 → 138
    Myb_DNA-binding; Myb-like DNA-binding domain
    pfam07988
    Location:269 → 313
    LMSTEN; LMSTEN motif
    pfam09316
    Location:518 → 683
    Cmyb_C; C-myb, C-terminal

  2. XM_004263794.3 → XP_004263842.1  transcriptional activator Myb isoform X3

    Related
    ENSOORP00010003191.1, ENSOORT00010004170.1
    Conserved Domains (4) summary
    smart00717
    Location:92 → 140
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    pfam00249
    Location:92 → 138
    Myb_DNA-binding; Myb-like DNA-binding domain
    pfam07988
    Location:269 → 313
    LMSTEN; LMSTEN motif
    pfam09316
    Location:401 → 530
    Cmyb_C; C-myb, C-terminal

  3. XM_004263792.3 → XP_004263840.1  transcriptional activator Myb isoform X1

    Related
    ENSOORP00010003188.1, ENSOORT00010004168.1
    Conserved Domains (4) summary
    smart00717
    Location:92 → 140
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    pfam00249
    Location:92 → 138
    Myb_DNA-binding; Myb-like DNA-binding domain
    pfam07988
    Location:269 → 313
    LMSTEN; LMSTEN motif
    pfam09316
    Location:401 → 562
    Cmyb_C; C-myb, C-terminal

  4. XM_033406706.2 → XP_033262597.1  transcriptional activator Myb isoform X2

    Conserved Domains (4) summary
    smart00717
    Location:20 → 68
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    COG5147
    Location:69 → 182
    REB1; Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning]
    pfam07988
    Location:249 → 293
    LMSTEN; LMSTEN motif
    pfam09316
    Location:382 → 542
    Cmyb_C; C-myb, C-terminal

  5. XM_033406716.2 → XP_033262607.1  transcriptional activator Myb isoform X2

    Conserved Domains (4) summary
    smart00717
    Location:20 → 68
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    COG5147
    Location:69 → 182
    REB1; Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning]
    pfam07988
    Location:249 → 293
    LMSTEN; LMSTEN motif
    pfam09316
    Location:382 → 542
    Cmyb_C; C-myb, C-terminal
Nucleotide Protein
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