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PTGES2 prostaglandin E synthase 2 [ Ovis aries (sheep) ]

Gene ID: 101109261, updated on 8-Mar-2024

Summary

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Gene symbol
PTGES2
Gene description
prostaglandin E synthase 2
See related
EnsemblRapid:ENSOARG00020014029
Gene type
protein coding
RefSeq status
MODEL
Organism
Ovis aries
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 3
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 3 NC_056056.1 (8129609..8135134)

Chromosome 3 - NC_056056.1Genomic Context describing neighboring genes Neighboring gene bublin coiled coil protein Neighboring gene lipocalin 2 Neighboring gene uncharacterized LOC132659550 Neighboring gene transfer RNA glycine (anticodon CCC) Neighboring gene solute carrier family 25 member 25

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_056056.1 Chromosome 3 Reference ARS-UI_Ramb_v3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Regulation of membrane-associated prostaglandin E2 synthase 1 in pregnant sheep intrauterine tissues by glucocorticoid and estradiol. Zhang Q, et al. Endocrinology, 2006 Aug. PMID 16690805

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables prostaglandin-E synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
prostaglandin E synthase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UI_Ramb_v3.0 Primary Assembly

Genomic

  1. NC_056056.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Range
    8129609..8135134
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027966397.2 → XP_027822198.1  prostaglandin E synthase 2

    UniProtKB/TrEMBL
    A0A6P7DTS5, W5PMJ1
    Related
    ENSOARP00020055451.1, ENSOART00020075030.1
    Conserved Domains (2) summary
    cd03197
    Location:221 → 369
    GST_C_mPGES2; C-terminal, alpha helical domain of microsomal Prostaglandin E synthase Type 2
    cd03040
    Location:98 → 174
    GST_N_mPGES2; GST_N family; microsomal Prostaglandin E synthase Type 2 (mPGES2) subfamily; mPGES2 is a membrane-anchored dimeric protein containing a CXXC motif which catalyzes the isomerization of PGH2 to PGE2. Unlike cytosolic PGE synthase (cPGES) and microsomal ...
Nucleotide Protein Strain
Heading Accession and Version

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