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NCK2 NCK adaptor protein 2 [ Felis catus (domestic cat) ]

Gene ID: 101099871, updated on 17-Aug-2024

Summary

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Official Symbol
NCK2
Official Full Name
NCK adaptor protein 2
Primary source
VGNC:VGNC:68428
See related
EnsemblRapid:ENSFCTG00005002947
Gene type
protein coding
RefSeq status
MODEL
Organism
Felis catus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: A3
Exon count:
7
Annotation release Status Assembly Chr Location
105 current F.catus_Fca126_mat1.0 (GCF_018350175.1) A3 NC_058370.1 (54596594..54751574, complement)
104 previous assembly Felis_catus_9.0 (GCF_000181335.3) A3 NC_018725.3 (57011133..57167077, complement)

Chromosome A3 - NC_058370.1Genomic Context describing neighboring genes Neighboring gene ECRG4 augurin precursor Neighboring gene uncharacterized LOC123384408 Neighboring gene uncharacterized LOC109498112 Neighboring gene uncharacterized LOC109498113

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of PERK-mediated unfolded protein response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of translation in response to endoplasmic reticulum stress IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cytoplasmic protein NCK2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Felis catus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference F.catus_Fca126_mat1.0 Primary Assembly

Genomic

  1. NC_058370.1 Reference F.catus_Fca126_mat1.0 Primary Assembly

    Range
    54596594..54751574 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023251544.2 → XP_023107312.1  cytoplasmic protein NCK2

    UniProtKB/TrEMBL
    M3VXW5
    Conserved Domains (4) summary
    cd10409
    Location:283 → 380
    SH2_Nck2; Src homology 2 (SH2) domain found in Nck
    cd11899
    Location:2 → 59
    SH3_Nck2_1; First Src Homology 3 domain of Nck2 adaptor protein
    cd11902
    Location:114 → 168
    SH3_Nck2_2; Second Src Homology 3 domain of Nck2 adaptor protein
    cd11903
    Location:198 → 256
    SH3_Nck2_3; Third Src Homology 3 domain of Nck2 adaptor protein

  2. XM_023251542.2 → XP_023107310.1  cytoplasmic protein NCK2

    UniProtKB/TrEMBL
    M3VXW5
    Conserved Domains (4) summary
    cd10409
    Location:283 → 380
    SH2_Nck2; Src homology 2 (SH2) domain found in Nck
    cd11899
    Location:2 → 59
    SH3_Nck2_1; First Src Homology 3 domain of Nck2 adaptor protein
    cd11902
    Location:114 → 168
    SH3_Nck2_2; Second Src Homology 3 domain of Nck2 adaptor protein
    cd11903
    Location:198 → 256
    SH3_Nck2_3; Third Src Homology 3 domain of Nck2 adaptor protein

  3. XM_023251543.2 → XP_023107311.1  cytoplasmic protein NCK2

    UniProtKB/TrEMBL
    M3VXW5
    Conserved Domains (4) summary
    cd10409
    Location:283 → 380
    SH2_Nck2; Src homology 2 (SH2) domain found in Nck
    cd11899
    Location:2 → 59
    SH3_Nck2_1; First Src Homology 3 domain of Nck2 adaptor protein
    cd11902
    Location:114 → 168
    SH3_Nck2_2; Second Src Homology 3 domain of Nck2 adaptor protein
    cd11903
    Location:198 → 256
    SH3_Nck2_3; Third Src Homology 3 domain of Nck2 adaptor protein

  4. XM_045053983.1 → XP_044909918.1  cytoplasmic protein NCK2

    UniProtKB/TrEMBL
    M3VXW5
    Related
    ENSFCTP00005005045.1, ENSFCTT00005007936.1
    Conserved Domains (4) summary
    cd10409
    Location:283 → 380
    SH2_Nck2; Src homology 2 (SH2) domain found in Nck
    cd11899
    Location:2 → 59
    SH3_Nck2_1; First Src Homology 3 domain of Nck2 adaptor protein
    cd11902
    Location:114 → 168
    SH3_Nck2_2; Second Src Homology 3 domain of Nck2 adaptor protein
    cd11903
    Location:198 → 256
    SH3_Nck2_3; Third Src Homology 3 domain of Nck2 adaptor protein
Nucleotide Protein
Heading Accession and Version

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