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CDT1 chromatin licensing and DNA replication factor 1 [ Felis catus (domestic cat) ]

Gene ID: 101098673, updated on 17-Aug-2024

Summary

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Official Symbol
CDT1
Official Full Name
chromatin licensing and DNA replication factor 1
Primary source
VGNC:VGNC:60721
See related
EnsemblRapid:ENSFCTG00005005906
Gene type
protein coding
RefSeq status
MODEL
Organism
Felis catus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: E2
Exon count:
10
Annotation release Status Assembly Chr Location
105 current F.catus_Fca126_mat1.0 (GCF_018350175.1) E2 NC_058382.1 (60732934..60737406)
104 previous assembly Felis_catus_9.0 (GCF_000181335.3) E2 NC_018737.3 (62988254..62992732)

Chromosome E2 - NC_058382.1Genomic Context describing neighboring genes Neighboring gene cytosolic thiouridylase subunit 2 Neighboring gene piezo type mechanosensitive ion channel component 1 (Er blood group) Neighboring gene uncharacterized LOC123382339 Neighboring gene adenine phosphoribosyltransferase Neighboring gene galactosamine (N-acetyl)-6-sulfatase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA polymerase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA replication checkpoint signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in DNA replication preinitiation complex assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mitotic cell cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of DNA-templated DNA replication initiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
DNA replication factor Cdt1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Felis catus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference F.catus_Fca126_mat1.0 Primary Assembly

Genomic

  1. NC_058382.1 Reference F.catus_Fca126_mat1.0 Primary Assembly

    Range
    60732934..60737406
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023245559.2 → XP_023101327.1  DNA replication factor Cdt1

    UniProtKB/TrEMBL
    A0A5F5Y4Q4, M3WI19
    Related
    ENSFCTP00005011359.1, ENSFCTT00005016564.1
    Conserved Domains (2) summary
    cd08674
    Location:166 → 350
    Cdt1_m; The middle winged helix fold of replication licensing factor Cdt1 binds geminin to inhibit binding of the MCM complex to origins of replication and DNA
    cd08767
    Location:410 → 531
    Cdt1_c; The C-terminal fold of replication licensing factor Cdt1 is essential for Cdt1 activity and directly interacts with MCM2-7 helicase
Nucleotide Protein
Heading Accession and Version

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