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BAK1 BCL2 antagonist/killer 1 [ Pan paniscus (pygmy chimpanzee) ]

Gene ID: 100983246, updated on 8-Mar-2024

Summary

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Gene symbol
BAK1
Gene description
BCL2 antagonist/killer 1
See related
Ensembl:ENSPPAG00000029631
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan paniscus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 5
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanPan1-v2.0_pri (GCF_029289425.2) 5 NC_073254.2 (48052701..48060642, complement)
RS_2023_05 previous assembly NHGRI_mPanPan1-v1.1-0.1.freeze_pri (GCF_029289425.1) 6 NC_073255.1 (43919864..43927610, complement)

Chromosome 5 - NC_073254.2Genomic Context describing neighboring genes Neighboring gene synaptic Ras GTPase activating protein 1 Neighboring gene cutA divalent cation tolerance homolog Neighboring gene zinc finger and BTB domain containing 9 Neighboring gene putative gametogenetin-binding protein 1 Neighboring gene putative uncharacterized protein encoded by LINC00336 Neighboring gene uncharacterized LOC130541587 Neighboring gene inositol 1,4,5-trisphosphate receptor type 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein homodimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in extrinsic apoptotic signaling pathway in absence of ligand IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intrinsic apoptotic signaling pathway in response to DNA damage IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrial outer membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
bcl-2 homologous antagonist/killer

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_029289425.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

Genomic

  1. NC_073254.2 Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

    Range
    48052701..48060642 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003808559.5 → XP_003808607.1  bcl-2 homologous antagonist/killer isoform X1

    See identical proteins and their annotated locations for XP_003808607.1

    UniProtKB/TrEMBL
    A0A2R9A6M3, A0A2R9A7S4
    Related
    ENSPPAP00000012940.1
    Conserved Domains (1) summary
    cd06845
    Location:29 → 183
    Bcl-2_like; Apoptosis regulator proteins of the Bcl-2 family, named after B-cell lymphoma 2. This alignment model spans what have been described as Bcl-2 homology regions BH1, BH2, BH3, and BH4. Many members of this family have an additional C-terminal transmembrane ...

  2. XM_034961863.3 → XP_034817754.1  bcl-2 homologous antagonist/killer isoform X2

    Conserved Domains (1) summary
    cd06845
    Location:2 → 124
    Bcl-2_like; Apoptosis regulator proteins of the Bcl-2 family, named after B-cell lymphoma 2. This alignment model spans what have been described as Bcl-2 homology regions BH1, BH2, BH3, and BH4. Many members of this family have an additional C-terminal transmembrane ...
Nucleotide Protein
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