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Acap2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 [ Cricetulus griseus (Chinese hamster) ]

Gene ID: 100760438, updated on 8-Mar-2024

Summary

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Gene symbol
Acap2
Gene description
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
See related
Ensembl:ENSCGRG00015022743
Gene type
protein coding
RefSeq status
MODEL
Organism
Cricetulus griseus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 4
Exon count:
24
Annotation release Status Assembly Chr Location
104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003613591.1 (718834..810092, complement)
104 current CriGri-PICRH-1.0 (GCF_003668045.3) 4 NC_048597.1 (58267458..58358639)

NW_003613591.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC100759851 Neighboring gene xyloside xylosyltransferase 1 Neighboring gene uncharacterized LOC107978135 Neighboring gene protein phosphatase 1 regulatory inhibitor subunit 2 Neighboring gene apolipoprotein D

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in endosome membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CriGri_1.0 Primary Assembly

Genomic

  1. NW_003613591.1 Reference CriGri_1.0 Primary Assembly

    Range
    718834..810092 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_007640465.3 → XP_007638655.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 isoform X2

    See identical proteins and their annotated locations for XP_007638655.1

    UniProtKB/TrEMBL
    A0A8C2M784, A0A9J7FW07
    Conserved Domains (7) summary
    cd07638
    Location:46 → 244
    BAR_ACAP2; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with Coiled-coil, ANK repeat and PH domain containing protein 2
    smart00105
    Location:429 → 544
    ArfGap; Putative GTP-ase activating proteins for the small GTPase, ARF
    cd00204
    Location:629 → 745
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd13250
    Location:296 → 392
    PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
    pfam00169
    Location:294 → 388
    PH; PH domain
    pfam12796
    Location:629 → 723
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:657 → 690
    ANK; ANK repeat [structural motif]

  2. XM_007640457.3 → XP_007638647.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 isoform X1

    See identical proteins and their annotated locations for XP_007638647.1

    UniProtKB/TrEMBL
    A0A8C2M784, A0A9J7FUG1
    Conserved Domains (7) summary
    cd07638
    Location:46 → 244
    BAR_ACAP2; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with Coiled-coil, ANK repeat and PH domain containing protein 2
    smart00105
    Location:436 → 551
    ArfGap; Putative GTP-ase activating proteins for the small GTPase, ARF
    cd00204
    Location:636 → 752
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd13250
    Location:296 → 399
    PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
    pfam00169
    Location:294 → 395
    PH; PH domain
    pfam12796
    Location:636 → 730
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:664 → 697
    ANK; ANK repeat [structural motif]

Alternate CriGri-PICRH-1.0

Genomic

  1. NC_048597.1 Alternate CriGri-PICRH-1.0

    Range
    58267458..58358639
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027412887.2 → XP_027268688.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C2M784, A0A9J7FUG1
    Related
    ENSCGRP00015047885.1, ENSCGRT00015072332.1

  2. XM_027412888.2 → XP_027268689.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A8C2M784, A0A9J7FW07
    Related
    ENSCGRP00015056822.1, ENSCGRT00015072033.1
Nucleotide Protein Strain
Heading Accession and Version

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