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Sirt6 sirtuin 6 [ Cricetulus griseus (Chinese hamster) ]

Gene ID: 100760117, updated on 8-Mar-2024

Summary

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Gene symbol
Sirt6
Gene description
sirtuin 6
See related
Ensembl:ENSCGRG00015022095
Gene type
protein coding
RefSeq status
MODEL
Organism
Cricetulus griseus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 5
Exon count:
9
Annotation release Status Assembly Chr Location
104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003614244.1 (256822..261077)
104 current CriGri-PICRH-1.0 (GCF_003668045.3) 5 NC_048598.1 (102382819..102387083, complement)

NW_003614244.1Genomic Context describing neighboring genes Neighboring gene cytokine receptor-like factor 3 Neighboring gene zinc finger protein 431 Neighboring gene ankyrin repeat domain 24 Neighboring gene TLE family member 6, subcortical maternal complex member Neighboring gene TLE family member 2, transcriptional corepressor

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Unraveling the Chinese hamster ovary cell line transcriptome by next-generation sequencing. Becker J, et al. J Biotechnol, 2011 Dec 10. PMID 21945585

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables NAD+ binding IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
NAD-dependent protein deacetylase sirtuin-6
Names
NAD-dependent deacetylase sirtuin-6

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CriGri_1.0 Primary Assembly

Genomic

  1. NW_003614244.1 Reference CriGri_1.0 Primary Assembly

    Range
    256822..261077
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027439325.2 → XP_027295126.1  NAD-dependent protein deacetylase sirtuin-6 isoform X1

    UniProtKB/TrEMBL
    A0A9J7G2W2

  2. XM_035458371.1 → XP_035314262.1  NAD-dependent protein deacetylase sirtuin-6 isoform X3

    UniProtKB/TrEMBL
    A0A9J7JYU6
    Conserved Domains (1) summary
    cl00195
    Location:45 → 250
    SIR2; SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+, ...

  3. XM_003506436.5 → XP_003506484.1  NAD-dependent protein deacetylase sirtuin-6 isoform X2

    See identical proteins and their annotated locations for XP_003506484.1

    UniProtKB/TrEMBL
    G3HSI4
    Conserved Domains (1) summary
    cd01410
    Location:45 → 257
    SIRT7; SIRT7: Eukaryotic and prokaryotic group (class4) which includes human sirtuin SIRT6, SIRT7, and several bacterial homologs; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent ...

  4. XM_035458372.1 → XP_035314263.1  NAD-dependent protein deacetylase sirtuin-6 isoform X4

    UniProtKB/TrEMBL
    A0A9J7K9L6
    Conserved Domains (1) summary
    cl00195
    Location:45 → 230
    SIR2; SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+, ...

  5. XM_027439326.2 → XP_027295127.1  NAD-dependent protein deacetylase sirtuin-6 isoform X5

    UniProtKB/TrEMBL
    A0A9J7G246

Alternate CriGri-PICRH-1.0

Genomic

  1. NC_048598.1 Alternate CriGri-PICRH-1.0

    Range
    102382819..102387083 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_035445559.1 → XP_035301450.1  NAD-dependent protein deacetylase sirtuin-6 isoform X4

    UniProtKB/TrEMBL
    A0A9J7K9L6
    Conserved Domains (1) summary
    cl00195
    Location:45 → 230
    SIR2; SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+, ...

  2. XM_027419195.2 → XP_027274996.1  NAD-dependent protein deacetylase sirtuin-6 isoform X2

    UniProtKB/TrEMBL
    G3HSI4
    Related
    ENSCGRP00015029277.2, ENSCGRT00015035822.2

  3. XM_035445558.1 → XP_035301449.1  NAD-dependent protein deacetylase sirtuin-6 isoform X3

    UniProtKB/TrEMBL
    A0A9J7JYU6
    Conserved Domains (1) summary
    cl00195
    Location:45 → 250
    SIR2; SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+, ...

  4. XM_027419194.2 → XP_027274995.1  NAD-dependent protein deacetylase sirtuin-6 isoform X1

    UniProtKB/TrEMBL
    A0A9J7G2W2

  5. XM_027419196.2 → XP_027274997.1  NAD-dependent protein deacetylase sirtuin-6 isoform X5

    UniProtKB/TrEMBL
    A0A9J7G246
Nucleotide Protein Strain
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