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Robo1 roundabout guidance receptor 1 [ Cavia porcellus (domestic guinea pig) ]

Gene ID: 100733124, updated on 8-Mar-2024

Summary

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Gene symbol
Robo1
Gene description
roundabout guidance receptor 1
See related
Ensembl:ENSCPOG00000010039
Gene type
protein coding
RefSeq status
MODEL
Organism
Cavia porcellus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae; Cavia
Orthologs
human mouse all
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Genomic context

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See Robo1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
33
Annotation release Status Assembly Chr Location
RS_2024_02 current mCavPor4.1 (GCF_034190915.1) Unplaced Scaffold NW_026947498.1 (26320775..27331724, complement)
103 previous assembly Cavpor3.0 (GCF_000151735.1) Unplaced Scaffold NT_176385.1 (11173670..11558963, complement)

NW_026947498.1Genomic Context describing neighboring genes Neighboring gene roundabout guidance receptor 2 Neighboring gene U6 spliceosomal RNA Neighboring gene kinesin-associated protein 3-like Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC134470559 Neighboring gene uncharacterized LOC134470560 Neighboring gene 1,4-alpha-glucan branching enzyme 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables axon guidance receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Roundabout signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in axon midline choice point recognition IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in homophilic cell adhesion via plasma membrane adhesion molecules IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in synapse organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in axon IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in neuronal cell body IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
roundabout homolog 1
Names
roundabout, axon guidance receptor, homolog 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_034190915.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mCavPor4.1

Genomic

  1. NW_026947498.1 Reference mCavPor4.1

    Range
    26320775..27331724 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063224749.1 → XP_063080819.1  roundabout homolog 1 isoform X2

  2. XM_063224750.1 → XP_063080820.1  roundabout homolog 1 isoform X3

  3. XM_063224748.1 → XP_063080818.1  roundabout homolog 1 isoform X1

  4. XM_063224753.1 → XP_063080823.1  roundabout homolog 1 isoform X7

  5. XM_063224751.1 → XP_063080821.1  roundabout homolog 1 isoform X4

  6. XM_063224752.1 → XP_063080822.1  roundabout homolog 1 isoform X6

  7. XM_023564910.2 → XP_023420678.1  roundabout homolog 1 isoform X5

    UniProtKB/TrEMBL
    H0VFZ6
    Related
    ENSCPOP00000009012.3
    Conserved Domains (7) summary
    cd05724
    Location:135 → 219
    Ig2_Robo; Second immunoglobulin (Ig)-like domain in Robo (roundabout) receptors
    cd05725
    Location:240 → 308
    Ig3_Robo; Third immunoglobulin (Ig)-like domain in Robo (roundabout) receptors
    cd05726
    Location:326 → 415
    Ig4_Robo; Third immunoglobulin (Ig)-like domain in Robo (roundabout) receptors
    cd07693
    Location:28 → 127
    Ig1_Robo; First immunoglobulin (Ig)-like domain in Robo (roundabout) receptors and similar proteins
    cd00063
    Location:522 → 608
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00041
    Location:739 → 825
    fn3; Fibronectin type III domain
    pfam13927
    Location:415 → 489
    Ig_3; Immunoglobulin domain
Nucleotide Protein
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