U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

adamts5 ADAM metallopeptidase with thrombospondin type 1 motif 5 [ Oreochromis niloticus (Nile tilapia) ]

Gene ID: 100694579, updated on 8-Mar-2024

Summary

Go to the top of the page Help
Gene symbol
adamts5
Gene description
ADAM metallopeptidase with thrombospondin type 1 motif 5
See related
Ensembl:ENSONIG00000012151
Gene type
protein coding
RefSeq status
MODEL
Organism
Oreochromis niloticus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini; Oreochromis
Expression
Broad expression in skin (RPKM 4.4), whole embryo (RPKM 3.7) and 6 other tissues See more
Orthologs
human zebrafish all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: LG23
Exon count:
8
Annotation release Status Assembly LG Location
104 current O_niloticus_UMD_NMBU (GCF_001858045.2) LG23 NC_031986.2 (11088301..11106461)
103 previous assembly ASM185804v2 (GCF_001858045.1) LG23 NC_031986.1 (33410080..33428238, complement)

Linkage Group LG23 - NC_031986.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102076658 Neighboring gene sodium- and chloride-dependent GABA transporter 2 Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif, 1 Neighboring gene cysteine/tyrosine-rich 1

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Oreochromis niloticus Transcriptome or Gene expression Oreochromis niloticus Transcriptome or Gene expression
  • Description: Oreochromis niloticus (Nile Tilapia) RNA sequencing from multiple tissues.
  • BioProject: PRJNA78915
  • Analysis date: Fri Dec 29 00:23:36 2017

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in extracellular matrix organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in collagen-containing extracellular matrix IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
A disintegrin and metalloproteinase with thrombospondin motifs 5

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Oreochromis niloticus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference O_niloticus_UMD_NMBU Primary Assembly

Genomic

  1. NC_031986.2 Reference O_niloticus_UMD_NMBU Primary Assembly

    Range
    11088301..11106461
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005450037.4 → XP_005450094.2  A disintegrin and metalloproteinase with thrombospondin motifs 5

    UniProtKB/TrEMBL
    A0A669CA66, I3K2F6
    Related
    ENSONIP00000015301.1, ENSONIT00000015314.2
    Conserved Domains (6) summary
    smart00209
    Location:565 → 617
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:263 → 468
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam05986
    Location:729 → 847
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam01562
    Location:47 → 163
    Pep_M12B_propep; Reprolysin family propeptide
    pfam17771
    Location:482 → 549
    ADAM_CR_2; ADAM cysteine-rich domain
    pfam19030
    Location:916 → 967
    TSP1_ADAMTS; Thrombospondin type 1 domain
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.