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GRK6 G protein-coupled receptor kinase 6 [ Canis lupus familiaris (dog) ]

Gene ID: 100684653, updated on 8-Mar-2024

Summary

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Official Symbol
GRK6provided by VGNC
Official Full Name
G protein-coupled receptor kinase 6provided by VGNC
Primary source
VGNC:VGNC:41506
See related
Ensembl:ENSCAFG00845009982
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See GRK6 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
17
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 4 NC_051808.1 (36293886..36309656, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 4 NC_006586.4 (35894854..35910623, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 4 NC_049225.1 (36814574..36830339, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 4 NC_049264.1 (36119132..36134901, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 4 NC_049745.1 (36305102..36320864, complement)

Chromosome 4 - NC_051808.1Genomic Context describing neighboring genes Neighboring gene drebrin 1 Neighboring gene proline rich 7, synaptic Neighboring gene uncharacterized LOC111095525 Neighboring gene coagulation factor XII Neighboring gene solute carrier family 34 member 1 Neighboring gene profilin 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables G protein-coupled receptor kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
G protein-coupled receptor kinase 6
XP_005619211.1
XP_038329484.1
XP_038329485.1
XP_038329486.1
XP_038349787.1
XP_038349803.1
XP_038390557.1
XP_038390558.1
XP_038390559.1
XP_038454869.1
XP_038454870.1
XP_038454871.1
XP_038519163.1
XP_038519164.1
XP_038519165.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051808.1 Reference ROS_Cfam_1.0

    Range
    36293886..36309656 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038663236.1 → XP_038519164.1  G protein-coupled receptor kinase 6 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KHW1, A0A8C0M5L1, A0A8I3NPS7
    Related
    ENSCAFP00845013672.1, ENSCAFT00845017565.1
    Conserved Domains (2) summary
    cd05630
    Location:185 → 469
    STKc_GRK6; Catalytic domain of the Serine/Threonine Kinase, G protein-coupled Receptor Kinase 6
    cl02565
    Location:35 → 179
    RGS; Regulator of G protein signaling (RGS) domain superfamily

  2. XM_038663235.1 → XP_038519163.1  G protein-coupled receptor kinase 6 isoform X1

    Conserved Domains (2) summary
    cd05630
    Location:198 → 482
    STKc_GRK6; Catalytic domain of the Serine/Threonine Kinase, G protein-coupled Receptor Kinase 6
    cl02565
    Location:48 → 192
    RGS; Regulator of G protein signaling (RGS) domain superfamily

  3. XM_038663237.1 → XP_038519165.1  G protein-coupled receptor kinase 6 isoform X3

    Conserved Domains (2) summary
    cd05630
    Location:198 → 482
    STKc_GRK6; Catalytic domain of the Serine/Threonine Kinase, G protein-coupled Receptor Kinase 6
    cl02565
    Location:48 → 192
    RGS; Regulator of G protein signaling (RGS) domain superfamily

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049264.1 Alternate UMICH_Zoey_3.1

    Range
    36119132..36134901 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038473557.1 → XP_038329485.1  G protein-coupled receptor kinase 6 isoform X2

    Conserved Domains (2) summary
    cd05630
    Location:185 → 469
    STKc_GRK6; Catalytic domain of the Serine/Threonine Kinase, G protein-coupled Receptor Kinase 6
    cl02565
    Location:35 → 179
    RGS; Regulator of G protein signaling (RGS) domain superfamily

  2. XM_038473556.1 → XP_038329484.1  G protein-coupled receptor kinase 6 isoform X1

    Conserved Domains (2) summary
    cd05630
    Location:198 → 482
    STKc_GRK6; Catalytic domain of the Serine/Threonine Kinase, G protein-coupled Receptor Kinase 6
    cl02565
    Location:48 → 192
    RGS; Regulator of G protein signaling (RGS) domain superfamily

  3. XM_038473558.1 → XP_038329486.1  G protein-coupled receptor kinase 6 isoform X3

    Conserved Domains (2) summary
    cd05630
    Location:198 → 482
    STKc_GRK6; Catalytic domain of the Serine/Threonine Kinase, G protein-coupled Receptor Kinase 6
    cl02565
    Location:48 → 192
    RGS; Regulator of G protein signaling (RGS) domain superfamily

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049745.1 Alternate UNSW_CanFamBas_1.0

    Range
    36305102..36320864 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038598942.1 → XP_038454870.1  G protein-coupled receptor kinase 6 isoform X2

    Conserved Domains (2) summary
    cd05630
    Location:185 → 469
    STKc_GRK6; Catalytic domain of the Serine/Threonine Kinase, G protein-coupled Receptor Kinase 6
    cl02565
    Location:35 → 179
    RGS; Regulator of G protein signaling (RGS) domain superfamily

  2. XM_038598941.1 → XP_038454869.1  G protein-coupled receptor kinase 6 isoform X1

    Conserved Domains (2) summary
    cd05630
    Location:198 → 482
    STKc_GRK6; Catalytic domain of the Serine/Threonine Kinase, G protein-coupled Receptor Kinase 6
    cl02565
    Location:48 → 192
    RGS; Regulator of G protein signaling (RGS) domain superfamily

  3. XM_038598943.1 → XP_038454871.1  G protein-coupled receptor kinase 6 isoform X3

    Conserved Domains (2) summary
    cd05630
    Location:198 → 482
    STKc_GRK6; Catalytic domain of the Serine/Threonine Kinase, G protein-coupled Receptor Kinase 6
    cl02565
    Location:48 → 192
    RGS; Regulator of G protein signaling (RGS) domain superfamily

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049225.1 Alternate UU_Cfam_GSD_1.0

    Range
    36814574..36830339 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038534630.1 → XP_038390558.1  G protein-coupled receptor kinase 6 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KHW1, A0A8C0M5L1, A0A8I3NPS7
    Conserved Domains (2) summary
    cd05630
    Location:185 → 469
    STKc_GRK6; Catalytic domain of the Serine/Threonine Kinase, G protein-coupled Receptor Kinase 6
    cl02565
    Location:35 → 179
    RGS; Regulator of G protein signaling (RGS) domain superfamily

  2. XM_038534629.1 → XP_038390557.1  G protein-coupled receptor kinase 6 isoform X1

    Conserved Domains (2) summary
    cd05630
    Location:198 → 482
    STKc_GRK6; Catalytic domain of the Serine/Threonine Kinase, G protein-coupled Receptor Kinase 6
    cl02565
    Location:48 → 192
    RGS; Regulator of G protein signaling (RGS) domain superfamily

  3. XM_038534631.1 → XP_038390559.1  G protein-coupled receptor kinase 6 isoform X3

    Conserved Domains (2) summary
    cd05630
    Location:198 → 482
    STKc_GRK6; Catalytic domain of the Serine/Threonine Kinase, G protein-coupled Receptor Kinase 6
    cl02565
    Location:48 → 192
    RGS; Regulator of G protein signaling (RGS) domain superfamily

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006586.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    35894854..35910623 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005619154.4 → XP_005619211.1  G protein-coupled receptor kinase 6 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KHW1, A0A8C0M5L1, A0A8I3NPS7
    Conserved Domains (2) summary
    cd05630
    Location:185 → 469
    STKc_GRK6; Catalytic domain of the Serine/Threonine Kinase, G protein-coupled Receptor Kinase 6
    cl02565
    Location:35 → 179
    RGS; Regulator of G protein signaling (RGS) domain superfamily

  2. XM_038493859.1 → XP_038349787.1  G protein-coupled receptor kinase 6 isoform X1

    Conserved Domains (2) summary
    cd05630
    Location:198 → 482
    STKc_GRK6; Catalytic domain of the Serine/Threonine Kinase, G protein-coupled Receptor Kinase 6
    cl02565
    Location:48 → 192
    RGS; Regulator of G protein signaling (RGS) domain superfamily

  3. XM_038493875.1 → XP_038349803.1  G protein-coupled receptor kinase 6 isoform X3

    Conserved Domains (2) summary
    cd05630
    Location:198 → 482
    STKc_GRK6; Catalytic domain of the Serine/Threonine Kinase, G protein-coupled Receptor Kinase 6
    cl02565
    Location:48 → 192
    RGS; Regulator of G protein signaling (RGS) domain superfamily
Nucleotide Protein
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