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RNF146 ring finger protein 146 [ Nomascus leucogenys (northern white-cheeked gibbon) ]

Gene ID: 100590342, updated on 8-Mar-2024

Summary

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Gene symbol
RNF146
Gene description
ring finger protein 146
See related
EnsemblRapid:ENSNLEG00000014130
Gene type
protein coding
RefSeq status
MODEL
Organism
Nomascus leucogenys
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae; Nomascus
Orthologs
human mouse all
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Genomic context

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See RNF146 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
5
Annotation release Status Assembly Chr Location
103 current Asia_NLE_v1 (GCF_006542625.1) 3 NC_044383.1 (113509515..113531785)
102 previous assembly Nleu_3.0 (GCF_000146795.2) 3 NC_019818.1 (114592438..114614708)

Chromosome 3 - NC_044383.1Genomic Context describing neighboring genes Neighboring gene 40S ribosomal protein S4 pseudogene Neighboring gene R-spondin 3 Neighboring gene ethylmalonyl-CoA decarboxylase 1 Neighboring gene 14-3-3 protein zeta/delta-like Neighboring gene 60S ribosomal protein L5-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables poly-ADP-D-ribose binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
E3 ubiquitin-protein ligase RNF146

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Nomascus leucogenys Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Asia_NLE_v1 Primary Assembly

Genomic

  1. NC_044383.1 Reference Asia_NLE_v1 Primary Assembly

    Range
    113509515..113531785
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003255676.4 → XP_003255724.1  E3 ubiquitin-protein ligase RNF146 isoform X2

    See identical proteins and their annotated locations for XP_003255724.1

    UniProtKB/TrEMBL
    G1RV88, M3ZCL9
    Related
    ENSNLEP00000017165.2, ENSNLET00000018028.3
    Conserved Domains (2) summary
    smart00678
    Location:104 → 176
    WWE; Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated proteolysis
    cd16546
    Location:36 → 75
    RING-HC_RNF146; RING finger, HC subclass, found in RING finger protein 146 (RNF146) and similar proteins

  2. XM_003255675.4 → XP_003255723.1  E3 ubiquitin-protein ligase RNF146 isoform X2

    See identical proteins and their annotated locations for XP_003255723.1

    UniProtKB/TrEMBL
    G1RV88, M3ZCL9
    Conserved Domains (2) summary
    smart00678
    Location:104 → 176
    WWE; Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated proteolysis
    cd16546
    Location:36 → 75
    RING-HC_RNF146; RING finger, HC subclass, found in RING finger protein 146 (RNF146) and similar proteins

  3. XM_030809648.1 → XP_030665508.1  E3 ubiquitin-protein ligase RNF146 isoform X3

    Related
    ENSNLEP00000052272.1, ENSNLET00000077764.1
    Conserved Domains (2) summary
    smart00678
    Location:103 → 175
    WWE; Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated proteolysis
    cd16546
    Location:35 → 74
    RING-HC_RNF146; RING finger, HC subclass, found in RING finger protein 146 (RNF146) and similar proteins

  4. XM_030809647.1 → XP_030665507.1  E3 ubiquitin-protein ligase RNF146 isoform X1

    Related
    ENSNLEP00000024456.2, ENSNLET00000032823.3
    Conserved Domains (2) summary
    smart00678
    Location:106 → 178
    WWE; Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated proteolysis
    cd16546
    Location:38 → 77
    RING-HC_RNF146; RING finger, HC subclass, found in RING finger protein 146 (RNF146) and similar proteins
Nucleotide Protein
Heading Accession and Version

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