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PDE8B phosphodiesterase 8B [ Sus scrofa (pig) ]

Gene ID: 100522306, updated on 8-Mar-2024

Summary

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Official Symbol
PDE8Bprovided by VGNC
Official Full Name
phosphodiesterase 8Bprovided by VGNC
Primary source
VGNC:VGNC:100321
See related
Ensembl:ENSSSCG00000014097
Gene type
protein coding
RefSeq status
MODEL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression
Broad expression in ovary (RPKM 8.3), subcutaneous adipose (RPKM 3.6) and 5 other tissues See more
Orthologs
human mouse all
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Genomic context

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See PDE8B in Genome Data Viewer
Location:
chromosome: 2
Exon count:
26
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 2 NC_010444.4 (86007190..86323796)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 2 NC_010444.3 (87703295..87929545)

Chromosome 2 - NC_010444.4Genomic Context describing neighboring genes Neighboring gene angiogenic factor with G-patch and FHA domains 1 Neighboring gene zinc finger BED-type containing 3 Neighboring gene NFU1 iron-sulfur cluster scaffold homolog, mitochondrial pseudogene Neighboring gene heat shock protein HSP 90-beta pseudogene Neighboring gene WD repeat domain 41 Neighboring gene uncharacterized LOC110259769 Neighboring gene orthopedia homeobox

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 3',5'-cyclic-AMP phosphodiesterase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010444.4 Reference Sscrofa11.1 Primary Assembly

    Range
    86007190..86323796
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021084468.1 → XP_020940127.1  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X5

    UniProtKB/TrEMBL
    A0A5G2Q8E4
    Related
    ENSSSCP00000060141.2, ENSSSCT00000073788.2
    Conserved Domains (2) summary
    pfam00233
    Location:550 → 797
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
    pfam13426
    Location:182 → 279
    PAS_9; PAS domain

  2. XM_021084469.1 → XP_020940128.1  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X6

    UniProtKB/TrEMBL
    A0A5G2Q8E4
    Conserved Domains (2) summary
    pfam00233
    Location:549 → 796
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
    pfam13426
    Location:181 → 278
    PAS_9; PAS domain

  3. XM_021084472.1 → XP_020940131.1  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X9

    UniProtKB/TrEMBL
    A0A5G2Q8E4
    Conserved Domains (2) summary
    pfam00233
    Location:509 → 756
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
    pfam13426
    Location:175 → 272
    PAS_9; PAS domain

  4. XM_021084470.1 → XP_020940129.1  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X7

    UniProtKB/TrEMBL
    A0A5G2Q8E4
    Conserved Domains (2) summary
    pfam00233
    Location:543 → 790
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
    pfam13426
    Location:175 → 272
    PAS_9; PAS domain

  5. XM_021084471.1 → XP_020940130.1  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X8

    UniProtKB/TrEMBL
    A0A5G2Q8E4
    Conserved Domains (2) summary
    pfam00233
    Location:542 → 789
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
    pfam13426
    Location:174 → 271
    PAS_9; PAS domain

  6. XM_021084465.1 → XP_020940124.1  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X1

    UniProtKB/TrEMBL
    A0A4X1SWK5
    Conserved Domains (3) summary
    pfam08629
    Location:1 → 47
    PDE8; PDE8 phosphodiesterase
    pfam00233
    Location:648 → 895
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
    pfam13426
    Location:280 → 377
    PAS_9; PAS domain

  7. XM_021084466.1 → XP_020940125.1  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X2

    UniProtKB/TrEMBL
    A0A4X1SWK5
    Conserved Domains (3) summary
    pfam08629
    Location:1 → 47
    PDE8; PDE8 phosphodiesterase
    pfam00233
    Location:647 → 894
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
    pfam13426
    Location:279 → 376
    PAS_9; PAS domain

  8. XM_013994908.2 → XP_013850362.2  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X3

    UniProtKB/TrEMBL
    A0A286ZWX2, A0A480L8H5, A0A4X1SWK5
    Related
    ENSSSCP00000036186.2, ENSSSCT00000038239.3
    Conserved Domains (3) summary
    pfam08629
    Location:1 → 47
    PDE8; PDE8 phosphodiesterase
    pfam00233
    Location:614 → 861
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
    pfam13426
    Location:280 → 377
    PAS_9; PAS domain

  9. XM_021084467.1 → XP_020940126.1  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X4

    UniProtKB/TrEMBL
    A0A4X1SWK5
    Conserved Domains (3) summary
    pfam08629
    Location:1 → 47
    PDE8; PDE8 phosphodiesterase
    pfam00233
    Location:613 → 860
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
    pfam13426
    Location:279 → 376
    PAS_9; PAS domain
Nucleotide Protein
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