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F2RL1 F2R like trypsin receptor 1 [ Sus scrofa (pig) ]

Gene ID: 100519703, updated on 8-Mar-2024

Summary

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Official Symbol
F2RL1provided by VGNC
Official Full Name
F2R like trypsin receptor 1provided by VGNC
Primary source
VGNC:VGNC:87861
See related
Ensembl:ENSSSCG00000014091
Gene type
protein coding
RefSeq status
MODEL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Also known as
PAR2
Expression
Biased expression in ovary (RPKM 8.9), lung (RPKM 5.3) and 4 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
2
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 2 NC_010444.4 (85732082..85747552)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 2 NC_010444.3 (87348813..87364248)

Chromosome 2 - NC_010444.4Genomic Context describing neighboring genes Neighboring gene IQ motif containing GTPase activating protein 2 Neighboring gene coagulation factor II thrombin receptor like 2 Neighboring gene coagulation factor II thrombin receptor Neighboring gene S100 calcium binding protein Z Neighboring gene corticotropin releasing hormone binding protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Proteinase-activated receptors 1 and 2 and the regulation of porcine coronary artery contractility: a role for distinct tyrosine kinase pathways. El-Daly M, et al. Br J Pharmacol, 2014 May. PMID 24506284, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. (Proteinase-activated receptors 1 and 2 (PAR1 and PAR2))PAR1/2 were found to mediate the regulation of coronary artery contractility.
    Title: Proteinase-activated receptors 1 and 2 and the regulation of porcine coronary artery contractility: a role for distinct tyrosine kinase pathways.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables thrombin-activated receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in blood coagulation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phospholipase C-activating G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of Rho protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in thrombin-activated receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
proteinase-activated receptor 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010444.4 Reference Sscrofa11.1 Primary Assembly

    Range
    85732082..85747552
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003123713.4 → XP_003123761.1  proteinase-activated receptor 2

    UniProtKB/TrEMBL
    A0A481C047, A0A8D0JA83, A0A8D1FLY9, F1S2H4
    Related
    ENSSSCP00000014983.2, ENSSSCT00000015392.5
    Conserved Domains (2) summary
    pfam00001
    Location:93 → 344
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:161 → 362
    7tm_4; Olfactory receptor
Nucleotide Protein
Heading Accession and Version

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